نتایج جستجو برای: intramolecular michael addition

تعداد نتایج: 747019  

Journal: :Catalysts 2023

3,4-dihydropyridin-2-ones are of considerable importance due to the large number these core structures exhibiting a diverse array biological and pharmacological activities. The Michael-type addition 1,3-dithiane-2-carbothioates α,β-unsaturated N-tosyl imines, followed by intramolecular annulation driven sulfur leaving group, provides practical reaction cascade for synthesis variety substituted ...

Journal: :Bulletin of the Chemical Society of Japan 1980

Journal: :Journal of the American Chemical Society 2005
Yujiro Hayashi Hiroaki Gotoh Tomohiro Tamura Hirofumi Yamaguchi Ryouhei Masui Mitsuru Shoji

Asymmetric intramolecular Michael reaction catalyzed by an organocatalyst derived from cysteine has been developed for the synthesis of chiral bicyclo[4.3.0]nonene and cis-disubstituted cyclopentane skeletons with a creation of three or two contiguous chiral centers in good yield with high diastereo- and excellent enantioselectivities.

The anticoagulant racemic warfarin is synthesized by the Michael addition of 4-hydroxycoumarin with benzalacetone in the present of equimolar amounts of imidazolium based ionic liquids [bmim] BF4 and [bmim] Br and other reaction solvents such as H2O, pyridine and ammonia in five different tests. Also synthesis of a derivative of warfarin (2-methyl-4-phenyl pyrano [3, 2-c] chromen-5(4H)-one) und...

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