It has been clearly established that the budding of the human immunodeficiency virus (HIV-1), a lentivirus, occurs specifically through the basolateral membrane in polarized epithelial cells. More recently, the signal was assigned to a tyrosine-based motif located in the intracytoplasmic domain of the envelope glycoprotein, as previously observed on various other viral and cellular basolateral ...

Immunoreceptor tyrosine-based inhibition motifs (ITIMs) consist of a 6-amino acid stretch (ILV)xYxx(LV). ITIMs are expressed in the intracytoplasmic domain of transmembrane receptors, which extinguish cell activation induced by receptors bearing immunoreceptor tyrosine-based activation motifs. The recent identification of new members of the ITIM-bearing receptor family (such as the signal-regul...

We report a case of papillary adenocarcinoma of the sigmoid colon with psammoma bodies and intracytoplasmic hyaline globules. The patient was a 59-year-old woman. The tumor showed central ulceration with smooth elevated ridges. Histologically, the tumor was composed of numerous large irregular tubular structures accompanying infolded papillary growth. The tumor cells showed cytoplasmic basophil...

Lungs and lymph nodes of 79 Atlantic bottlenose dolphins (Tursiops truncatus) that died from 6 August 1987 to 16 April 1988 along the Atlantic coasts of New Jersey, Virginia, and Florida (USA) were examined histologically and were tested for the presence of morbillivirus antigen by an immunoperoxidase technique. Lung lesions included areas of interstitial pneumonia characterized by varying comb...

QUESTION UNDER STUDY The feasibility and the potential advantages of separating X-chromosome bearing spermatozoa for the prevention of a severe X-chromosome linked disorder with the use of intracytoplasmic sperm injection are presented. METHOD A carrier of muscular dystrophy type Becker was treated with intracytoplasmic sperm injection, using spermatozoa previously stained with the Hoechst dy...

background: recent studies of uterine contractility in ivf�embryo transfer led us to consider an alternative, and possibly complementary, explanation for the high implantation rates of blastocysts. it has been demonstrated that myometrial contractile activity influences embryo implantation, possibly through mechanical displacement of embryos. objective: the aim of this study was to examine the ...