OBJECT Intracranial subependymomas are rarely reported due to their extremely low incidence. Knowledge about subependymomas is therefore poor. This study aimed to analyze the incidence and clinical, radiological, and pathological features of intracranial subependymomas. METHODS Approximately 60,000 intracranial tumors were surgically treated at Beijing Tiantan Hospital between 2003 and 2013. ...

Orbital neoplasms with associated bone erosions and intracranial extension are generally considered suspicious for malignancies. Here, we describe the clinical and radiological findings, as well as the surgical management of two extraordinary cases, in which such bony perforations with subsequent intracranial tumor growth resulted from benign angiomatous orbital neoplasms. Two female patients, ...

Gamma Knife has become a major therapeutic method for intracranial meningiomas, vascular malformations and schwannomas with exact effect. In recent years an increasing number of delayed complications after Gamma Knife surgery have been reported, such as secondary tumors, cystic changes or cyst formation. But angiomatous lesion and delayed cyst formation after Gamma Knife for intracranial lesion...

Background: Intracranial meningiomas are rare in individuals under age 30 years. The purpose of this study was to analyze the demographics and clinical features of intracranial meningiomas in individuals under age 30 years. Methods: A retrospective analysis of clinical, radiographic, and pathology data of patients under age 30 years who presented with an intracranial meningioma was performed. R...

abstract a patient with a 3-month history of headache refractory to pain medication was admitted. the ct scan and mri showed evidence of a posterior fossa mass. this was pathologically confirmed as an extra medullary plasmacytoma (emp). he had a pathologic fracture of the left humerus 7 years ago while the radiologist was unaware at the time of diagnosis. a solitary bone plasmacytoma (sbp) was ...

BACKGROUND Chemotherapeutic drugs and newly developed therapeutic monoclonal antibodies are adequately delivered to most solid and systemic tumors. However, drug delivery into primary brain tumors and metastases is impeded by the blood-brain tumor barrier (BTB), significantly limiting drug use in brain cancer treatment. METHODOLOGY/PRINCIPAL FINDINGS We examined the effect of phosphodiesteras...

The effort that occurs during the Valsalva maneuver provokes a raise in intracranial pressure and may decompensate patients with increased intracranial pressure. The aims of this study were to evaluate the incidence of intestinal constipation in the preoperative period of patients with intracranial tumors and establish a relationship between constipation and intracranial pressure decompensation...

Purpose The aim of this pilot study was to assess the clinical feasibility, diagnostic yield, advantages, and disadvantages of structured reporting for routine MRI-reading in patients with primary diagnosis of intracranial tumors as compared to traditional neuroradiological free text reporting. Methods A structured MRI reporting template was developed covering pathological, anatomical, and fu...