conclusions the pattern of pretreatment with o2 could change this potential and highly protective strategy against cp-induced nephropathy to an ineffective or even mildly deteriorating one. therefore, o2 administration before cp injection to patients with cancer, for therapeutic purposes or as a preconditioning approach, should be performed and investigated with caution until exact effects of d...

UNLABELLED The molecular networks underlying the lung response to hypoxia are not fully understood. We employed systems biology approaches to study temporal effects of intermittent or sustained hypoxia on gene expression in rat lungs. We obtained gene expression profiles from rats exposed to intermittent or sustained hypoxia lasting 0-30 days and identified differentially expressed genes, their...