Interleukin-1β (IL-1β) level is modulated during multiple stress reactions both in brain structures involved in hypothalamic-pituitary-adrenal (HPA) axis regulation and peripheral systems. Multiple distinct stressors induce different IL-1β and HPA axis responses. The purpose of the present study was to determine if the effect of prior repeated restraint stress on IL-1β levels in prefrontal cort...

Kouyanqing Granule (KYQG) is a traditional Chinese herbal formula composed of Flos lonicerae (FL), Radix scrophulariae (RS), Radix ophiopogonis (RO), Radix asparagi (RA), and Radix et rhizoma glycyrrhizae (RG). In contrast with the typical method of separating and then biologicalily testing the components individually, this study was designed to establish an approach in order to define the core...

Introduction Interleukin-1β (IL-1β), interleukin-1 receptor antagonist (IL-1ra) and interleukin-6 (IL-6) contribute to the pathogenesis of ulcerative colitis (UC). The aim of our study was to evaluate the serum and stool IL-1β, IL-1ra and IL-6 concentrations as potential prognostic factors in children with UC. Material and methods Thirty-eight children with UC (20 active, 18 inactive) and 14 ...

Research Objective This study was aimed to determine the main ingredients of Huajie Xiaoliu Formula (HJF) and investigate anti-colon cancer effect its combination with Tegafur, Gimeracil, Oteracil Potassium Capsules (S-1) in vivo as well preliminarily explore possible mechanism. Materials Methods The chemical composition HJF determined by ultra-high performance liquid chromatography quadrupole ...

Liver fibrosis is the main pathological feature of various chronic liver diseases that can progress to cirrhosis. However, no effective treatment strategy for available. Phytic acid (PA) a natural plant compound found in cereals, legumes, and rapeseed. Currently, there are few reports on its relationship with fibrosis. Herein, we explored effects PA In this study, model was constructed by intra...

background: nepeta dschuparensis bornm (np) is used as a medicinal herb in iran. in traditional medicine, this herb is extensively employed for curing ailments such as cardiovascular diseases. np has antioxidant and anti-inflammatory properties. this project examined the effects of the np extract on cyclooxygenase-2 (cox-2) and interleukin-1β (il-1β) protein levels and its efficacy in neuroprot...

Periodontitis is inflammation of the periodontal tissue that can cause progressive damage to ligament and alveolar bone. Clinical examination determine degree bone using a probe instrument or probing. Cellular activity in gingival crevicular fluid thought be biomarker inflammatory status tissue. immune responses suggest role cytokines pathogenesis gingivitis periodontitis. The observed this stu...

This study was aimed to monitor water pullution of Uzuncayir Dam Lake using the changes of IL-6, IL1β and TNF-α levels in Capoeta umbla (Heckel, 1843) liver tissue at ten stations in March and September 2011. In this study C. umbla (Heckel, 1843) was used as the indicator organism. Tumor necrosis factor-α (TNF-α), interlekuin1β (IL-1β) and interleukin-6 (IL-6) levels were determined in samples ...