Background Hypermelanosis includes a diverse group of genetic and acquired skin anomalies that appear as darker, hyperpigmented areas. Melasma, in particular, is a hypermelanotic condition that affects sun-exposed skin in females. Whether this condition is acquired or genetic is still controversial. However, it clearly correlates with exposure to UV light, a genetic predisposition, and hormonal...

BACKGROUND Intense pulse light (IPL) treatment currently represents one of the most popular non-ablative photodamage skin treatments. Recent anecdotal evidence suggests that aminolevulonic acid (ALA) photodynamic therapy using IPL as a light source is superior to IPL alone for photorejuvenation. METHODS Seven adult subjects (six women, one man) with minimal photodamage were treated with full ...

BACKGROUND Unwanted hair growth remains a therapeutic challenge and there is a considerable need for an effective and safe treatment modality. OBJECTIVE From an evidence-based view to summarize efficacy and adverse effects from hair removal with ruby, alexandrite, diode, and Nd:YAG lasers and intense pulsed light (IPL). METHODS Original publications of controlled clinical trials were identi...

71 in 2008 in which Diaz et al 9 described a patient treated with adalimumab for rheumatoid arthritis whose lesions developed 2 months after the start of biologic treatment; and the third reported by Adenis-Lamarre et al 10 in 2009 in a patient with rheumatoid arthritis receiving adalimumab who developed skin lesions and was subsequently diagnosed with M chelonae infection. Our case differs fro...

A faun tail is abnormal lumbar hypertrichosis that is characterized by a wide, often triangular or lozenge-shaped patch of coarse hair, and this hair is usually several inches long. Faun tail is a rare entity. A 36-year-old male presented with a triangular shaped hair tuft with terminal hair on the lumbosacral area, and he'd had this unusual hair since birth. There were no neurologic signs or a...

Background: Intense pulsed light (IPL) and laser treatment parameters should be high enough to sufficiently damage target lesions while minimizing collateral damage to surrounding tissue. Fitzpatrick Skin Typing, a common assessment tool for these treatments, does not directly account for the density of melanin, a highly absorbing chromophore typically located in the epidermis. Quantification o...

BACKGROUND The adjunctive use of 5-aminolevulinic acid (5-ALA) with intense pulsed-light (IPL) treatments has been suggested to increase the benefit of IPL for photoaging; however, to our knowledge, no controlled trials have been performed. DESIGN A prospective, randomized, controlled, split-face study was designed. Twenty subjects participated in a series of 3 split-face treatments 3 weeks a...

PURPOSE The aim of this study was to estimate the efficacy of intense pulsed light (IPL), followed by meibomian gland expression (MGX), for reducing the number and severity of signs and symptoms of dry eye disease (DED) secondary to meibomian gland dysfunction (MGD). PATIENTS AND METHODS In a prospective study conducted in two sites, 40 subjects (80 eyes) with moderate to severe MGD were enro...