BACKGROUND Previous studies have demonstrated that aerobic exercise training and weight loss have independent effects on insulin-stimulated glucose disposal (ISGD). We hypothesized that ad libitum consumption of a high-carbohydrate diet would result in weight loss and improved ISGD, and that aerobic exercise training would facilitate greater improvements in ISGD compared with diet alone. METH...

INTRODUCTION In patients affected by insulin resistance (IR), metformin (MET) therapy has been shown to exert its positive effects by improving glucose tolerance and preventing the evolution to diabetes. Recently, it was shown that the addition of metformin to physical training did not improve sensitivity to insulin or peak oxygen consumption (peak VO2). The purpose of this study was to establi...

Diabetes mellitus is the most common metabolic diseases. It is estimated that its worldwide prevalence will reach to 21% up to 2050. In Iran the prevalence of diabetes is estimated to be about 14%. It divided in two categories: type 1 and type 2. Diabetes type 1 is due to absolute deficiency of insulin secretion, and type 2 characterised by resistances to insulin and its inadequate compensation...

ABSTRACT Background and Objectives: Obesity is a global health problem that could lead to cardiovascular disease, diabetes and cancer. Polygenic obesity is caused by multiple factors, such as lack of exercise and excess food intake. In this study, we evaluated effects of 12 weeks of high-intensity interval training (HIIT) and isocratic moderate-intensity training (MIT) on anthropometric indice...

objective: polycystic ovary syndrome (pcos) is the most common endocrinopathy in women of reproductive age characterized by the presence of polycystic ovaries, menstrual dysfunction and biochemical or clinical hyperandrogenism. lifestyle modification is important in treatment of obese and overweight women with pcos. this study was performed to evaluate the benefit of aerobic exercise training o...

background: the aim of this study was to investigate the effects of exercise training on maximum aerobic capacity, resting heart rate (rhr), blood pressure and anthropometric variables of postmenopausal women with breast cancer. methods : twenty nine women with breast cancer who received surgery, chemotherapy and radiotherapy with current hormone therapy were divided into two groups; interventi...