objective(s): the aim of this study was to observe the influence of phytoestrogen α-zearalanol on ovariectomy-induced postmenopausal osteoporosis in rats. materials and methods:40 sd female rats were randomly divided into four groups: sham group, ovx group (ovariectomized and fed estrogen), α-zearalanol group (ovariectomized and fed α-zearalanol) and untreated group (ovariectomized). three week...

Introduction: Osteoporosis is a bone disease in which there is a reduction in the amount of bone mineral content leading to an increase in the risk of bone fractures. The affected individuals not only have to go through lots of pain and suffering but this disease also results in high economic costs to the society due to a large number of fractures.  A timely and accurate diagnosis of this disea...

Fourteen Angus heifers (210 +/- 6 kg initial BW) were allotted randomly to either a low P (LP: .12% P, DM basis) or an adequate P (AP: .20% P, DM basis) diet fed for 14 to 16 mo under drylot conditions on concrete floors to determine the influence of dietary P on chemical, physical, and mechanical properties of bone. Three weeks postpartum, after 14 to 16 mo on their diets, heifers were slaught...

Trace minerals such as zinc, copper, and manganese are essential cofactors for hundreds of cellular enzymes and transcription factors in all animal species, and thus participate in a wide variety of biochemical processes. Immune development and response, tissue and bone development and integrity, protection against oxidative stress, and cellular growth and division are just a few examples. Defi...

We compared the mechanical properties of 'ordinary' bovine bone, the highly mineralized bone of the rostrum of the whale Mesoplodon densirostris, and mother of pearl (nacre) of the pearl oyster Pinctada margaritifera. The rostrum and the nacre are similar in having very little organic material. However, the rostral bone is much weaker and more brittle than nacre, which in these properties is cl...

PURPOSE Collagen peptides (CPs) and calcium citrate are commonly used as bone health supplements for treating osteoporosis. However, it remains unknown whether the combination of oral bovine CPs with calcium citrate is more effective than administration of either agent alone. METHODS Forty 12-week-old Sprague-Dawley rats were randomly divided into five groups (n = 8) for once-daily intragastr...