OBJECTIVES The aim of the study was to evaluate analgesic efficacy and tolerability of patient-controlled analgesia (PCA) with intravenous morphine. MATERIAL AND METHODS Our observational study included 50 women who underwent a Misgav-Ladach or modified Misgav-Ladach cesarean section. Automated PCA infusion device (Medima S-PCA Syringe Pump, Medima, Krakow, Poland) was used for postoperative ...

Background. A treatment algorithm for sickle cell disease (SCD) pain in adults presenting to a single emergency department (ED) was developed prioritizing initiation of patient controlled analgesia (PCA) for patients awaiting hospitalization. Objectives. Evaluate the proportion of ED visits in which PCA was started in the ED. Methods. A two-year retrospective chart review of consecutive SCD pai...

Background The aim is to compare the clinical effect of three different concentrations of levobupivacaine (0.25%, 0.125%, and 0.0625%) on the sensory and motor block characteristics and mode of delivery during epidural labor analgesia. We also studied the pharmacokinetic profile of the three concentrations during labor. Materials and Methods Sixty pregnant females undergoing normal vaginal de...

Background: Prolactin (PRL) appears to play a role in the pathogenesis of autoimmune diseases. Limited evidence showed an association between serum PRL levels and the activity of pemphigus vulgaris (PV). This study intends to determine PRL level changes in pemphigus patients during therapy and its correlation with disease type and severity. Methods: In this cohort study, we measured serum PRL l...

Objective: The effect of general anesthesia combined with epidural analgesia on post-operative recovery was investigated to improve the therapeutic effectiveness of laparoscopic radical resection of rectal carcinoma. Methods: Eighty patients who underwent laparoscopic radical resection of rectal carcinoma in our hospital from February 2016 to February 2017 were selected according to their hospi...

THE concept of preemptive analgesia to reduce the magnitude and duration of postoperative pain was paved in 1983 by Woolf, who showed evidence for a central component of postinjury pain hypersensitivity in experimental studies. Subsequently, an overwhelming amount of experimental data demonstrated that various antinociceptive techniques applied before injury were more effective in reducing the ...

introduction: this study was done to compare the efficacy of interlesional injection of glucantime method and cryotherapy with interlesional injection in treatment of cutaneous leishmaniasis in qom province. methods: in this randomized controlled trial patients were randomly allocated in the two arms of the study:one receiving interalesional glucantime injection weekly and the other receiving b...