BACKGROUND Dermatomyositis is an autoimmune disease of unknown etiology characterized by inflammation of the skin and muscles. Several medications have been implicated in the development of dermatomyositis; however, the disease has rarely been linked to the use of tumor necrosis factor (TNF) inhibitors. We report 4 cases of dermatomyositis that developed or were exacerbated by exposure to the T...

INTRODUCTION Atrial fi brillation (AF), the most common cardiac arrhythmia, is encountered in clinical practice with ever-increasing frequency.1 Older data suggest that the lifetime risk of AF in men and women older than 40 years of age is approximately one in four.2 The prevalence of AF has most likely increased due to the aging of the “baby-boomers” (AF is overwhelmingly a disease of age) and...

We present the case of a 70-year-old woman found to have a prothrombin time (PT) of 26.8 seconds (s) and an activated partial thromboplastin time (PTT) of 71 s prior to an elective endoscopic retrograde cholangiopancreatography for symptomatic choledocholithiasis. She had no personal or family history of bleeding, thrombosis, autoimmune diseases, miscarriages, recent surgery or antibiotic use, ...

Edoxaban: an investigational factor Xa inhibitor.

triple negative breast cancers (tnbcs) are associated with aggressive course, higher rates of visceral and central nervous system metastases and lower survival rate than hormone receptor positive. once metastasis has occurred, a median survival was approximately one year. currently, chemotherapy in tnbc is similar to other her2- negative breast cancers but in the near future, it will revolution...