OBJECTIVE Evaluation of the time required until a change in the basal insulin infusion rate with an insulin pump induces subsequent changes in the metabolic effect. RESEARCH DESIGN AND METHODS In this euglycemic glucose clamp study, 10 male subjects with type 1 diabetes received three different subcutaneous insulin infusion rates (0.5, 1.0, and 2.0 units/h; for 4 h each) of insulin lispro (IL) ...

Increased glucose and choline uptake are hallmarks of cancer. We investigated whether the conversion [2H9]choline alone together with that [6,6?-2H2]glucose can be assessed in tumors via deuterium metabolic imaging (DMI) after administering these compounds. Therefore, human renal carcinoma cells were grown subcutaneously mice. Isoflurane anesthetized mice IV infused MR magnet for ~20 s ~0.2 mL ...

We hypothesized chemotherapy infusion related reaction might be predictable according to continuous monitoring of heart rate recorded by a wearable device. In this study we propose deep learning model that predicts patient level symptoms per minute during infusion. prospectively enrolled patients with cancer who will receive and at high risk for reaction. During infusion, 1 interval was from sm...

BACKGROUND AND OBJECTIVES Intraosseous (IO) access has been used with good results in emergency situations, when venous access is not available for fluids and drugs infusion. The objective of this study was to evaluate IO a useful technique for anesthesia and fluids infusion during hemodynamic studies and when peripheral intravascular access is unobtainable. The setting was an university hospit...

Studies were performed on 20 male adult rats to investigate the effects of chronic intermittent infusion of lipid and physiological emulsifier into the distal small intestine on stomach to caecum transit time (SCTT) of the head of a test meal. SCTT was measured using environmental hydrogen analysis. Ileal lipid infusion normally delays gastric emptying and small intestinal transit (p < 0.001), ...

Background: Hypoglycemia is a condition when blood glucose level is lower than 70 mg/dl in people without diabetes. The symptoms of hypoglycemia include tachycardia, sweating, pallor, pupillary dilatation. Hypoglycemia is a non-lethal and often preventable clinical problem in non-diabetic patients that can occur during fasting or after dining. Case presentation: A 52 years old man referred to ...