introduction: the novel development of the (hba) sperm- hyaluronan binding assay has now been routinely used in some laboratories worldwide to predict sperm maturity and functionality. the purpose of this study was to evaluate the correlation between hba score and histone deficiency, protamine content and dna fragmentation. methods: during april- march 2012 patients who were enrolled at shiraz-...

Background: Exposure to certain drugs and toxins plays an important role in male infertility. Even fancy using of illegal drugs is an important factor in evaluation of male infertility. There is evidence in previous literature that this drug has harmful effects on fertility, but data based on evidence is limited. The purpose of this study was to evaluate the infertile couples in one of the infe...

Background: Infertility and its treatment involve a physical and emotional burden for both women and men, and that burden contributes to high drop-out rates from treatment. Lack of patient-centredness of care can cause patients to drop out from treatment for non-medical reasons. However, in order to provide patient-centred fertility care, an insight into the patient’s perspective on fertility c...

Advancements in assisted reproductive technology (ART) has increased the nurses' contribution to the provision of ART services. The present descriptive cross-sectional study aimed to determine essential care skills for nurses working at the selected infertility clinics in Tehran, Iran, based on their perspectives within 2016-2017. A total of 59 nurses were selected via a convenience sampling me...

OBJECTIVE To evaluate a new fully automated assay measuring antimüllerian hormone (AMH; Roche Elecsys) against antral follicle count in women of reproductive age. DESIGN Prospective cohort study. SETTING Hospital infertility clinics and academic centers. PATIENT(S) Four hundred fifty-one women aged 18 to 44 years, with regular menstrual cycles. INTERVENTION(S) None. MAIN OUTCOME MEASU...

Reproductive aging is characterized by a marked decline in oocyte quality that contributes to infertility, miscarriages, and birth defects. This decline is multifactorial, and the underlying mechanisms are under active investigation. Here, we performed RNA-Seq on individual growing follicles from reproductively young and old mice to identify age-dependent functions in oocytes. This unbiased app...

BACKGROUND As demand for infertility services by older women continues to grow, because achievable in vitro fertilization (IVF) outcomes are widely underestimated, most fertility centers do not offer maximal treatment options with use of autologous oocytes. Limited data suggest that clinical IVF outcomes in excess of what the American Society for Reproductive Medicine (ASRM) considers "futile" ...