The abstract is poorly written and complete abstract to be rewritten Background: Tannins extracted from immature fruits of Terminalia chebula Fructus Retz. are considered to be effective components to promote wound healing. This study aims to study optimal extraction and purification technology (OEPT) of tannins and study the use of the drug for the treatment of a cutaneuous wound of rat as wel...

INTRODUCTION Infection is a major threat to wound healing and a leading cause of graft loss in patients undergoing meshed skin grafts (MSGs). Therefore, topical antisepsis is important in the overall treatment scheme. METHODS An exploratory satellite group of 14 patients with infected MSGs were enrolled as part of a prospective, randomized, controlled, parallel-group, open-label, pilot Phase ...

The occurrence of post-operative wound infection was studied respectively over an eight month period in the University Hospital, Kuala Lumpur. One hundred and seventy four (3.4%) surgical wounds out of 5129 operations became infected. The clean wound infection rate was 2.9%, rising to 5.4% and 12.2% for clean-contaminated and contaminated surgical wounds respectively. Of the wound infections, 8...

The prevalence of antibiotic-resistant bacteria such as methicillin-resistant Staphylococcus aureus is rapidly increasing in healthcare facilities and spreading to the community. Methicillin-resistant S. aureus colonize the skin and open wounds and can interfere with wound healing. Recent studies have shown that ultraviolet light C can kill antibiotic-resistant strains of bacteria such as methi...

Branhamella catarrhalis was isolated from sputum, tracheal secretions, and a nonhealing and infected thoracic surgical wound in a 59-year-old woman who had a history of a chronic, interstitial fibrosis and who had undergone an open lung biopsy procedure. The patient's upper respiratory tract was the likely source of the organism. To our knowledge, this is the first report of a wound infection c...

Surgical site infections (SSIs) are a significant source of morbidity, mortality, and cost associated with small animal surgery. The most well-established strategies to reduce the impact of SSI are preventive, focusing on bolstering host immunity while decreasing wound contamination during surgery. When SSI is identified, the use of consistent definitions and culture-based therapy help to facil...

Lymphocele is a common complication after kidney transplantation. Although superinfection is a rare event, it generates a difficult management problem; generally, open surgical drainage is the preferred method of treatment but it may lead to complicated postoperative course and prolonged healing time. Negative pressure wound therapy showed promising outcomes in various surgical disciplines and ...

Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium Clostridium botulinum and sometimes by strains of Clostridium butyricum and Clostridium baratii. There are three main forms of botulism: foodborne botulism, caused by eating foods containing the botulinum toxin; wound botulism, caused by toxin produced in a wound infected with C. botulinum...

Dear Editors, Vacuum-assisted closure (VAC) devices provide negative pressure wound therapy (NPWT), and are currently employed frequently in the management of complex wounds. NPWT has been shown to improve clinical outcomes significantly. Proposed mechanisms of action for this wound management system include providing strain, which promotes more rapid wound closure by encouraging perfusion, fib...

The present study assessed the suitability of the streptozotocin-treated diabetic rat as a model for the study of diabetes-impaired wound healing. The distribution of three antibiotics, ampicillin, benzylpenicillin, and flucloxacillin, in wound and adjacent tissue sites on the abdomens and legs of normal and diabetic rats was determined 30 min after intravenous administration of a single bolus ...