This case report alerts to the existence of atypical forms of cutaneous leishmaniasis (CL). A woman with nodular cutaneous lesions over a neck with papules and pustules located deep in the hypodermis that formed plaques with subcutaneous induration and satellite papules was confirmed to have CL. After confirmation, the patient was treated with remission of the lesions, scarring and thickening o...

SETTING Six selected districts in Northern India. OBJECTIVES To find out the trend in Annual risk of tuberculous infection (ARTI) in north India. STUDY DESIGN Two rounds of community level surveys were conducted during 2000-2001 and 2009-10 respectively. Representative samples of children 1-9 years of age were tuberculin tested and maximum transverse diameter of induration was recorded in m...

Anal strictures with fibrotic induration have been shown to develop in up to 50% of all patients with Crohn's disease (CD) with anal ulceration. We evaluate the technical feasibility, safety and long-term efficacy of bougie dilation for a subgroup of patients with symptomatic Crohn's-related fibrotic anal strictures. Bougie dilation is simple to perform, relatively inexpensive and has a low ris...

A case of sarcoidosis, unusual in that it was confined to the tongue, is reported in a 50 year-old female. The condition resolved after 1 year of steroid therapy and excision of fibrous tethering bands. Intra-oral sarcoidosis should be considered in the differential diagnosis of lingual swelling and induration.

The allergic reactions of dermal induration and hyperthermia were compared in tuberculin-hypersensitive calves. Tuberculins prepared from Mycobacterium avium, M. bovis, and M. paratuberculosis were administered intradermally and the responses were compared. The indurations from immediate and delayed hypersensitivity reactions were readily distinguishable, but the hyperthermic responses appeared...

BACKGROUND African hospitals have experienced major increases in admissions for tuberculosis, but they are ill-equipped to prevent institutional transmission. We compared institutional rates and community rates of tuberculin skin test (TST) conversion in Harare, Zimbabwe. METHODS We conducted a cohort study of TST conversion 6, 12, and 18 months into training among 159 nursing and 195 polytec...

STUDY OBJECTIVES To assess the validity of purified protein derivative (PPD) readings by patients and trained health-care professionals as compared with a calibrated model. DESIGN AND PARTICIPANTS Survey of a group of patients, nurses, medical assistants, and physicians at five neighborhood health centers in the Bronx, NY. INTERVENTIONS Participants were asked to read a calibrated model wit...

Experiments were carried out in the skin of patients with leprosy to examine whether suppressor cell populations either exist in the skin of multibacillary lepromatous leprosy patients, can be activated with antigen, or are induced to emigrate into a cutaneous site from the circulation. For this purpose, purified protein derivative of tuberculin, a delayed-type antigen that generates a cell-med...

After Mantoux testing with purified protein derivative (PPD) equivalent to 5 tuberculin units (TU), a 28 yr old man developed extensive erythema, induration and proximal lymphangitis. This is the only such case observed after Mantoux testing in approximately 500,000 subjects during 10 yrs in the Greek Army.