Background: Earlier studies on the effect of constant electro-acupuncture (EA) treatments in rats with drug-induced polycystic ovary syndrome (PCOS), has been shown to revise the hormones and neurotransmitter levels. Aim: The present study was conducted with the aim to test the hypothesis that repeated EA treatment modulates Epinephrine (EPI) and Norepinephrine (NE) level of PCOS and anovulatio...

The ovarian surface epithelium (OSE) is a monolayer of cells that surround the ovary and accommodate repeated tear and repair in response to ovulation. OSE cells are thought to be the progenitors of 90% of ovarian cancers. Currently, the total amount of proliferation of the OSE has not been reported in response to one ovulatory event. In this study, proliferation of the OSE was quantified in re...

BACKGROUND Our objective was to explore the impact of a single dose of an aromatase inhibitor (letrozole) administered at defined times of the follicular phase or immediately after ovulation on dominant follicle development, luteogenesis and new follicle wave emergence. METHODS A prospective pilot study using a randomized complete block, controlled, open label design was conducted at an acade...

background: currently clomiphene citrate is the first-line treatment to induce ovulation in women with polycystic ovarian syndrome (pcos). surgical therapy with laparoscopic ovarian drilling (lod) may avoid or reduce the need for gonadotropins.   objective: to determine the effectiveness and safety of lod compared with ovulation induction in subfertile women with clomiphene-resistant pcos.   se...

Ovulation is the complex, inflammatory-like process by which the cumulus oocyte complex (COC) is released from a mature, preovulatory follicle through a rupture site at the ovarian surface and requires expression of genes that generate and stabilize the expanded extracellular COC matrix. Gene profiling analyses of COCs at selected time intervals during ovulation revealed that many genes associa...

The musk shrew, Suncus murinus, is an induced ovulator, the cumulus oophorus of which is unusual in several respects: it has no matrix, it always induces the acrosome reaction and it appears to be essential for fertilization. The present study documents distinctive features of the cumulus oophorus before and after ovulation, and of copulation-induced maturation of the ovulatory follicle, which ...

The purpose of the studies reported in this thesis was to provide a better understanding of the effects of purified ovulation-inducing factor (OIF) from llama seminal plasma in reflex ovulators (lama glama) and spontaneous ovulators (Bos taurus). The objective of the first study was to determine if the dose of OIF of llama seminal plasma required to elicit ovulation is physiologically relevant,...

introduction: melatonin acts as an indirect antioxidant and is a powerful direct free radical scavenger and direct responses to melatonin in the gonads are detected. this study aims to investigate the influence of different doses of melatonin on preantral follicle development and oogenesis of in vitro cultured mouse ovarian follicles. materials and methods: preantral follicles with diameters of...

The Damaraland mole-rat is a eusocial, subterranean rodent that exhibits a seasonal breeding. Non-reproductive females show physiological suppression of reproduction whilst in the confines of the natal colony. This study set out to investigate whether dispersing female Damaraland mole-rats exhibit induced or spontaneous ovulation. Fifteen non-reproductive females were removed from their natal c...

Gonadotropins are responsible for maturation of the ovarian follicle and the oocyte. Ovulation is the ultimate step in this process and involves disintegration of the follicular wall and subsequent release of an oocyte into the oviduct. These events are triggered by a surge of luteinizing hormone (LH). Genes expressed in the ovary, that respond to LH, are likely to be involved in the biochemica...