The population of elderly persons is growing with extraordinary rapidity. Although the majority enjoys good health, many older people suffer from multiple illnesses and significant disability. They tend to exhibit great medical complexity and vulnerability; have illnesses with atypical and obscure presentations; suffer major cognitive, affective, and functional problems; are especially vulnerab...

BACKGROUND The number of out-of-hours calls to general practitioners (GPs) has increased steadily during the past 20 years. The proportion of inappropriate calls are reportedly increasing but we know very little about how GPs judge a call to be appropriate or inappropriate. AIM To determine the factors that influence GPs' perceptions of the appropriateness or inappropriateness of out-of-hours...

The aim of this study was to determine the role played by vigilance on the anaerobic performance recorded during a Wingate test performed at the bathyphase (nadir) of the circadian rhythmicity. Twenty active male participants performed a 60-s Wingate test at 6 a.m. during 3 test sessions in counter-balanced order the day after either (i) a normal reference night, (ii) a total sleep deprivation ...

discussion neurobrucellosis is a rare presentation of brucellosis and should be considered when neurological problems cannot be explained by other etiology especially in endemic areas. introduction brucellosis is a zoonotic infection with high distribution all over the world and has many clinical manifestations, one of which is neurobrucellosis (nb). case presentation our case was a 78-year-old...

fluoxetine, a widely used antidepressant, can affect the serum sodium level. the aim of this study was to evaluate and compare changes in the serum sodium level of depressive patients taking fluoxetine according to age.this quasi-experimental study was conducted on 126 patients with depression, dividing the patients into two age groups of 15 to 35 years, and above 55 years, who referred to psyc...

BACKGROUND Scientific evidence on treatments of chronic diseases in patients 85 years old or older is very limited, as is available information on inappropriate prescription (IP) and its associated factors. The study aimed to describe medicine prescription, potentially inappropriate medicines (PIM) and potentially prescribing omissions (PPO) and their associated factors on this population. ME...

BACKGROUND Very little research thus far has examined the decision making that underlies inappropriate social behavior (ISB) post-TBI (traumatic brain injury). OBJECTIVES To verify the usefulness of a new instrument, the Social Responding Task, for investigating whether, in social decision making, individuals with TBI, who present inappropriate social behavior (ISB), have difficulty anticipat...

Laparoscopy is increasingly selected instead of the laparotomies at the last three decades. The earliest indications of laparoscopies were mostly for gynaecological treatments and cholecystectomies (Cunningham, 1998). Since then, spectrum has been expanding. Increasing laparoscopy experience caused expansion of the indications and, contrary to this, declining the contraindications. So, it can a...

The syndrome of inappropriate secretion of TSH was the term originally coined to indicate two forms of central hyperthyroidism, i.e. thyrotropin (TSH)-secreting pituitary adenomas (TSHomas) and resistance to thyroid hormone action (RTH). Both forms are characterized by high levels of free thyroxine (FT4) and free triiodothyronine (FT3) in the presence of measurable TSH concentrations, a biochem...

Inappropriate prescribing (IP) in older patients is highly prevalent and is associated with an increased risk of adverse drug events (ADEs), morbidity, mortality and healthcare utilisation. Consequently, IP is a major safety concern and with changing population demographics, it is likely to become even more prevalent in the future. IP can be detected using explicit or implicit prescribing indic...