نتایج جستجو برای: in vivo toxicity
تعداد نتایج: 16999427 فیلتر نتایج به سال:
برای بررسی بیان ژن های cslyc و csbch دخیل در سنتز کروسین در کالوسهای حاصل از جداکشت خامه و گلپوش زعفران crocus sativus از تکنیک واکنش زنجیره پلی مرازی نسخه برداری معکوس (rt-pcr) استفاده شد. این روش بر روی کالوس های حاصل از جداکشت خامه و گلپوش غنچه گلی زعفران سه مزرعه شاهرود، مردآباد کرج و تربت حیدریه انجام شد و در نهایت نتایج حاصل به لحاظ شدت بیان ژن ها از تکنیک synchronize با یکدیگر مقایسه شدن...
Background and purpose: There are few treatment options available for treatment of toxoplasmosis and effective drugs have serious toxic effects. In this study, the in vivo and in vitro anti-toxoplasma activities of Heracleum persicum and Foeniculum vulgare fruits essential oils were investigated. Materials and methods: In vitro, Vero cells were incubated with different concentrations of essent...
Objective(s): P-glycoprotein (P-gp) is an efflux protein, the overexpression of which has been associated with multidrug resistance in various cancers. Although siRNA delivery to reverse P-gp expression may be promising for sensitizing of tumor cells to cytotoxic drugs, the therapeutic use of siRNA requires effective carriers that can deliver siRNA intracellularly with minimal toxicity on targe...
Background and purpose: Studies showed that biocompatible and biodegradable materials in tissue engineering can be used to heal wounds. The aim of this study was to fabricate polyurethane/royal jelly/hyaluronic acid scaffold with suitable biological properties for wound healing using electrospinning method. Materials and methods: In this applied experimental study, to make a nanofiber scaffold...
background: cyclosporine a (csa) is a potent immunosuppressant drug with therapeutic and toxic actions. the use of csa is limited by its toxicity. several researchers had proposed that oxidative stress could play an important role in csa-induced toxicity. arbutin has recently been shown to possess antioxidative and free radical scavenging abilities.the present study was designed to investigate ...
In modern medical practice, toxicity studies are essential in assessment of safety of extracts or drugs used in clinical medicine. The interaction of the toxin or its metabolite with cellular constituents may bring about significant changes in hematological parameters. These alterations may be rapid or slow and often cause a change in structure and function of the affected tissues. In clinical ...
OBJECTIVE To investigate the toxicity of methanol extract of various parts (Root, Stem, Leaf, Flower and Fruit) of Lantana camara (L. Camara) in Artemia salina. METHODS The methanol extracts of L. camara were tested for in vivo brine shrimp lethality assay. RESULTS All the tested extract exhibited very low toxicity on brine shrimp larva. The results showed that the root extract was the most...
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