Abstract Background Self-expanding nitinol stent (SENS) implantation is commonly oversized in the superficial femoral artery (SFA), and leads to chronic outward force (COF) in-stent restenosis (ISR). This study aimed investigate impact of COF oversizing SENS on ISR SFA. Methods In patients with implanted SFA, intimal hyperplasia especially between proximal segment distal was evaluated by quanti...

BACKGROUND Coronary artery stents are used for the treatment of acute or threatening vessel occlusion complicating coronary angioplasty or for prevention of restenosis after angioplasty. The current randomized trial compared the procedural outcome and long-term patency of 2 different flexible stents in unselected lesion morphology. METHODS The study population consisted of consecutive patient...

OBJECTIVES This study aimed to clarify the role of the angiotensin-converting enzyme (ACE) gene polymorphism in the development of in-stent restenosis. BACKGROUND In-stent restenosis occurs after treatment of coronary artery stenosis in 12% to 32% of coronary interventions with stents. Experimental and clinical studies have suggested that the deletion/insertion (D/I) polymorphism of the ACE g...

Drug-coated balloon has been developed as an alternative to drug-eluting stents for in-stent restenosis but the performance of drug infusion balloon in such setting has not been previously described. We present a case of particularly aggressive in-stent restenosis after drug eluting stent implantation treated with a new kind of drug infusion balloon developed in order to overcome the impossibil...

OBJECTIVE In this case-match study, we evaluated the impact of the CYP2C19*2 polymorphism in the occurrence of in-stent restenosis during a 1-year follow-up period despite adequate dual anti-platelet therapy in Iranian patients having undergone percutaneous coronary intervention (PCI). METHODS This study, conducted at a tertiary referral heart center in Tehran, recruited 100 patients: 50 pati...

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main source(s): Cardiovascular Imaging Research Group, Medical Centre, Semmelweis University. Introduction The improved spatial resolution photon-counting detector CT (PCD-CT) allows better image quality and less artefacts even in high-density structures, such as coronary artery stents. Purpose Ou...

OBJECTIVES This quantitative angiographic and intravascular ultrasound study determined the mechanisms of acute lumen enlargement and recurrent restenosis after rotational atherectomy (RA) with adjunct percutaneous transluminal coronary angioplasty in the treatment of diffuse in-stent restenosis (ISR). BACKGROUND In-stent restenosis remains a significant clinical problem for which optimal tre...

Instent restenosis (ISR) has been a key factor that restricts the further use of intraoronary stents. And the mechanical interaction between the stent and the artery has been indicated as one of the significant causes for the activation of stent-related restenosis. However, there is very little quantitative information about the interaction of stent with artery. In order to improve the general ...

BACKGROUND Fractional flow reserve predicts cardiac events after coronary stent implantation. The aim of the present study was to assess the 9-month angiographic in-stent restenosis rate in the setting of optimal stenting and a persisting gradient distal to the stent as assessed by a pressure wire pullback recording in the entire length of the artery. METHODS AND RESULTS In 98 patients with a...

Abstract More and more researchers pay attention to the method of using stents treats intracranial aneurysms through way minimally invasive surgery. Due individual differences between patients complexity stenosis lesion, there is not an acknowledged criterion on stenting scheme, which mainly depends clinicians’ experience. Otherwise, inappropriate scheme may lead severe complications such as in...