background: flat urothelial lesions comprise a spectrum of morphologic changes ranging from reactive atypia to carcinoma in situ (cis). urothelial dysplasia and cis are associated with the recurrence and progression of urothelial carcinoma. distinguishing cis and dysplasia from reactive atypia based on histolopathogical features alone is often difficult. using different immunohistochemical mark...

knowledge of the orientation of horizontal in situ stresses is important to some areas of oil and gas field development plans. borehole breakouts observed in image logs and drilling-induced fractures are the main parameters for the determination of the stresses’ directions in situ. in this work, the orientations of borehole breakouts were investigated as a function of depth in oil wells a and b...

the present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. fourier transform infrared spectroscopy (ftir) and differential scannin...

purpose : to assess the outcomes of laser in situ keratomileusis (lasik) in patients with multiple sclerosis (ms) methods : 15 eyes of 8 patients with ms (2 men and 6 women) who referred for myopia treatment (with or without astigmatism) were undergone lasik. after refractive and visual acuity examinations, topographic and pachymetry screening, intraocular pressure (iop) measurement, biomicrosc...

hydrogels are introduced to modem medicine as novel materials suitable for a variety ofbiomedical applications. studying hydrogels as novel biomaterials has become a fast-developingand exciting research field during the last two decades. these interesting biomaterials have found awide range of application including contact lenses, vehicles for drug delivery and scaffold in tissueengineering and...

abstract  background: spondylolysis and spondylolisthesis can be associated with significant  low back pain, especially in physically active adolescents. non-operative management  is usually successful in improving symptoms, but surgical intervention is  occasionally required. the aim of this study was to determine the effect of in situ posterolateral  fusion in the treatment of refractory case...

malignant papillary neoplasms of the breast comprise a number of microscopically distinct lesions, where apocrine metaplasia is commonly found in papillomas compared to other papillary lesions including papillary carcinomas. however, association of apocrine metaplasia in papilloma with ductal carcinoma in situ (dcis) is not very well defined. the lesions with apocrine metaplasia are not only di...