We report an extreme morphological difference between Drosophila sechellia and related species of the pattern of hairs on first-instar larvae. On the dorsum of most species, the posterior region of the anterior compartment of most segments is covered by a carpet of fine hairs. In D. sechellia, these hairs have been lost and replaced with naked cuticle. Genetic mapping experiments and interspeci...

Only a few Drosophila melanogaster germline sex determination genes are known, and there have been no systematic screens to identify new genes involved in this important biological process. The ovarian phenotypes produced by females mutant for dominant alleles of the ovo gene are modified in flies with altered doses of other loci involved in germline sex determination in Drosophila (Sex-lethal+...

AIMS To describe the abundance of major phyla and some genera in the gut microbiota of individuals according to dietary habits and examine their associations with inflammatory markers, insulin resistance, and cardiovascular risk profile. METHODS A total of 268 non-diabetic individuals were stratified into groups of dietary types (strict vegetarians, lacto-ovo-vegetarians, and omnivores). The ...

Nutraceuticals are food ingredients that provide extra health advantages expand above their nutritional value. comprise amino acids, antioxidants, minerals, vitamins, probiotics, prebiotics, synbiotics, enzymes, organic fatty medicinal plants, etc. Recently, nutraceuticals have acquired much attention in poultry industry by reason of potential effects on establishing the normal physiological...

BACKGROUND The developmental mechanisms underlying the persistence of myocardial accessory atrioventricular pathways (APs) that bypass the annulus fibrosis are mainly unknown. In the present study, we investigated the role of epicardium-derived cells (EPDCs) in annulus fibrosis formation and the occurrence of APs. METHODS AND RESULTS EPDC migration was mechanically inhibited by in ovo microsu...

Plasmid DNA (pDNA)-based vaccines have emerged as effective subunit vaccines against viral and bacterial pathogens. In this study, a DNA vaccine, namely plasmid internal ribosome entry site-HN/F, was applied in ovo against Newcastle disease (ND). Vaccination was carried out using the DNA vaccine alone or as a mixture of the pDNA and dextran-spermine (D-SPM), a nanoparticle used for pDNA deliver...

In Drosophila, compatibility between the sexually differentiated state of the soma and the sex chromosome constitution of the germline is required for normal gametogenesis. In this study, we defined important aspects of the soma-germline interactions controlling early oogenesis. In particular, the sex-specific germline activity of the ovarian tumor promoter was found to be dependent upon somati...