Many isothiocysanates (ITC) are promising cancer-preventive agents, and induction of apoptosis is one of their underlying mechanisms of action. We recently found that caspase-9 was preferentially activated over other initiator caspases in human bladder cancer UM-UC-3 cells. We report here that caspase-9 activation is the major step leading to ITC-induced apoptosis in this cell line. More import...

A broth macrodilution method following the recommendations established by the National Committee for Clinical Laboratory Standards was used to compare the in vitro activity of posaconazole (PCZ) with that of itraconazole (ITC) against 30 clinical isolates of dermatophytes belonging to six different species. In terms of MICs, PCZ showed an activity equal to that of ITC. MICs of PCZ at which 50% ...

Recently ITC-irst (Interactive Sensory System division) and University of Pavia (Medical Informatics Labs) are working together to realize an intelligent (adaptive) dialogue system with language understanding capabilities. In this framework, some telemedicine services able to handle multimodal interactions (i.e. input/output can be provided by both voice and/or other devices such as: keyboard, ...

The concept of sustainable development (SD) was introduced in the “Our Common Future” report, launched 1987, which influenced emergence many studies related to role played by organizations as actors supporting SD. SD is a consolidated concept; however, since political, social, and natural events have occurred on our planet, impacted companies’ behaviors. However, diversity research from differe...

Whereas much is known about the visual shape selectivity of neurons in the inferior temporal cortex (ITC), less is known about the role of visual learning in the development and refinement of ITC shape selectivity. To address this, we trained monkeys to perform a visual categorization task with a parametric set of highly familiar stimuli. During training, the stimuli were always presented at th...

Policy evaluation is central to economic data analysis, but economists mostly work with observational in view of limited opportunities carry out controlled experiments. In the potential outcome framework, panel approach (Hsiao et al., 2012) constructs counterfactual by exploiting correlation between cross-sectional units data. The choice control units, a key step its implementation, nevertheles...

Abstract Science aims to build and advance general theories from empirical data. This process is complicated by the immense volume of data scientific in some domains, for example field health behavior change. Especially, a systematic mapping between theoretical constructs lacking. We propose toolbox establish that mapping. adopted modeling approach based on literature surveys elicit requirement...

Dietary isothiocyanates (ITCs) found in cruciferous vegetables (Brassica spp.) has been reported to reduce cancer risk by inducing phase II conjugating enzymes, in particular glutathione S-transferases (GSTs). This case-control study was aimed at determining associations between dietary ITCs, GSTs polymorphisms and risk habits (cigarette smoking, alcohol drinking and betel-quid chewing) with or...

A powerful and useful Data-Flow Visual Programming Language (DFVPL) must provide the necessary programming constructs to deal with complex problems. The main purpose of this paper is to give a contribution to the debate on DFVPL constructs by presenting the solutions we devised for the VIPERS language. Another purpose of the paper is to illustrate the methodology we developed in order to start ...

The study's aim was to examine factors that may influence health information managers in the adoption of electronic health records. The Technology Acceptance Model (TAM) served as theoretical foundation for this quantitative study. Hospital health information managers in Arkansas were queried as to the constructs of perceived usefulness, perceived ease of use, and behavior intention. The study ...