In vitro studies have revealed that T cell activation occurs during the formation of either dynamic or stable interactions with antigen-presenting cells (APC), and the respective cell junctions have been referred to as immunological kinapses and synapses. However, the relevance and molecular dynamics of kinapses and synapses remain to be established in vivo. Using two-photon imaging, we tracked...

Hydrops fetalis is defined by the accumulation of fluids in serous membranes (pleurisy, ascites, pericarditis...), it a rare condition; its etiologies are divided into immunological and non-immunological. Supraventricular tachycardia remains known cause, non-immunological, but difficult to manage.
 In this article we report case newborn with hydrops secondary supraventricular tachycardia, ...

BACKGROUND Feline immunodeficiency virus (FIV) and human immunodeficiency virus (HIV) are recently identified lentiviruses that cause progressive immune decline and ultimately death in infected cats and humans. It is of great interest to understand how to prevent immune system collapse caused by these lentiviruses. We recently described that disease caused by a virulent FIV strain in cats can b...

Immunofluorescence is an immunological method used to demonstrate the presence of antigen and antibodies in tissues or serum. Immunofluorescence techniques have become indispensable in modern pathology laboratories and have greatly contributed to the diagnosis, treatment and understanding of autoimmune bullous diseases, hereditary bullous diseases, collagen-vascular diseases, many inflammatory ...

Immunofluorescent techniques have been used extensively to detect the presence of antinuclear factors (ANF) in sera from patients with systemic lupus erythematosus and related disorders. Furthermore, morphological differences in the character of nuclear immunofluorescence have been considered to be of clinical as well as immunological significance (Casals, Friou, and Teague, 1963; Burnham, Fine...

Splenic cysts are rare lesions with around 800 cases reported in the world literature. Traditionally splenectomy was the treatment of choice. However, with the recognition of the important immunological function of the spleen, new techniques to preserve splenic function have been developed. This case emphasizes that in selected cases splenic preservation is appropriate.

BACKGROUND Tuberculous spondylodiscitis is one the many manifestations of active tuberculosis (TB) and can result following primary infection or, more frequently, from reactivation of active TB in subjects with latent TB. Definitive diagnosis of tuberculous spondylodiscitis requires the identification of Mycobacterium tuberculosis in the biological sample following microbiological analysis. A...