نتایج جستجو برای: immunological factors
تعداد نتایج: 1109733 فیلتر نتایج به سال:
Increasing evidence suggests that Alzheimer's disease pathogenesis is not restricted to the neuronal compartment, but includes strong interactions with immunological mechanisms in the brain. Misfolded and aggregated proteins bind to pattern recognition receptors on microglia and astroglia, and trigger an innate immune response characterised by release of inflammatory mediators, which contribute...
Crohn's disease is a rare with chronic relapsing course. Usually begins at young age influenced by environmental, genetic, and immunological factors. Patients mostly have only intestinal changes. In addition to the gut, other organs, such as skin, joints, liver, kidneys can be affected. The type of treatment choice drugs depends on severity disease.
The immunological synapse is a specialized cell-cell junction between T cell and antigen-presenting cell surfaces. It is characterized by a central cluster of antigen receptors, a ring of integrin family adhesion molecules, and temporal stability over hours. The role of this specific organization in signaling for T cell activation has been controversial. We use in vitro and in silico experiment...
Identifying prognostic factors in rectal cancer is very valuable for choosing the method of treatment. Prognostic factors play an important role in making decision of margin of surgery, treating with preor postoperative radiochemotherapy. In last few years, apart from traditional clinical and histopathological factors, also genetic, biochemical and immunological factors there are taken in the c...
BACKGROUND In resource constrained settings, immunological assessment through CD4 count is used to assess response to first line Highly Active Antiretroviral Therapy (HAART). In this study, we aim to investigate factors associated with immunological treatment failure. METHODS A matched case-control study design was used. Cases were subjects who already experienced immunological treatment fail...
Muscular dystrophy (MD) describes generalized progressive muscular weakness due to the wasting of muscle fibers. While this is an umbrella term used to describe a wide range of muscle wasting diseases, the two types that have been most extensively mathematically modeled are Duchenne’s (DMD) and Becker’s (BMD), with DMD being the most common childhood form of MD. Developing mathematical models t...
Objective: The objective of this study was to examine the clinical and immunological factors influencing sialometry in xerostomia patients. Method: The association between sialometry and other clinical examinations were investigated in a cross-sectional study. A total of 179 dry mouth patients showing hyposalivation who underwent a clinical examination were enrolled in this study. Multiple regr...
the major aim of this study was to investigate the relationship between social and cultural capital and efl students’ critical thinking skills. this study takes this relationship in to account to see if people with different sociocultural status are different regarding their critical thinking skills. to this end, 160 university students majoring in english language and literature, english trans...
PURPOSE Allergic diseases are triggered by Th2-mediated immune reactions to allergens and orchestrated by various immunological factors, including immune cells and cytokines. Although many reports have suggested that childhood is the critical period in the onset of allergic diseases and aging leads to alter the susceptibility of an individual to allergic diseases, age-related changes in various...
Beta Thalassemia major patients receive repeated transfusions in order to compensate anemia and use desferal to remove iron overload. Comparing immunoglobulins and complement components in the serum of these patients with normal range shows a significant increase (P<0.001) in IgG, IgA and IgM and a decrease in C3c and C4. The regression analysis confirms a relation between the numbers of transf...
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