Aconitum kusnezoffii used as an analgesic and anti-inflammatory. It is often not only in Mongolian medicine but also traditional Chinese medicine. However, there are few studies on its impact of inflammatory cytokines. This study explored the effects vitro human colon cancer (Caco-2) cells. Cytotoxicity was assessed by measuring expression IL-1β, IL-6, IL-8, TNF-α enzyme-linked immunosorbent as...

A significant fraction of IL-8 in lung fluids from patients with the acute lung injury (ALI) is associated with anti-IL-8 autoantibodies (anti-IL-8:IL-8 complexes), and lung fluid concentrations of these complexes correlate with development and outcome of ALI. In this study, we examined whether anti-IL-8:IL-8 complexes exhibit proinflammatory activity in vitro. These complexes were purified fro...

The aim of this research was to study the effect of exogenous interleukin (IL)-8, IL-1 and IL-8 + IL-1 on uterine contractions in rabbits. Four equal groups of non-pregnant rabbits (n = 24) were investigated using either placebo or experimental drugs in the form of vaginal suppositories. The suppositories contained human recombinant IL-8 (200 ng), IL-1 (200 ng), IL-8 (200 ng) + IL-1 (200 ng) or...

Despite existing studies on pathogenetic role of cytokine (CK) system in lung damage pneumonia, there are still controversial issues cytokine-mediated processes that lead to the prolongation inflammatory process tissue this pathology. The article presents study profile bronchoalveolar secretion (BAS) prolonged course community-acquired pneumonia (CAP). To achieve purpose research, patients with...