background: the activity and toxicity of etoposide in women with recurrent ovarian cancer was evaluated in a case series of women with recurrent ovarian cancer who had measurable disease, methods: all patients had plior platinum-based chemotherapy and developed progressive disease, etoposide was given as 50mg/day for 21 days every 4 weeks until progression of disease or prohibitive toxicity, be...

background : gestational trophoblastic neoplasia (gtn) disease is excessive and inappropriate proliferation of trophoblast after termination of the pregnancy. many attempts have been made to improve follow-up procedures, but no studies have evaluated human chorionic gonadotrophin (hcg) as a post treatment indicator. thus we aimed to know β-hcg variability in post treatment pregnancies.   method...

we aimed to investigate the effects of dietary combination of honey and ardeh on chemotherapy-induced complications in patients with acute myeloid leukemia (aml).a total of 107 aml patients who underwent chemotherapy for at least 30 consecutive days were recruited to this double-blind randomized placebo-controlled clinical-trial which was conducted in the imam reza and ghaem teaching hospitals ...

introduction: endometrial cancer is the most common pelvic malignancy in women. approximately 7,000 women die from this disease every year. although most patients can be treated with appropriate therapies, there is insufficient data regarding the choice of the best adjuvant therapy after a surgical procedure in advanced endometrial cancer cases. it seems that radiotherapy or chemotherapy alone ...

objectives the aim of this study was to investigate the effects of local cryotherapy on the intensity of chemotherapy-induced oral mucositis in autologous bone marrow transplantation patients. patients and methods in this single, blinded, randomized clinical trial, 29 patients undergoing stem cell transplantation in iran were selected by convenience sampling, and randomly allocated to control (...

introduction: today, due to the broad spectrum of pediatric cancers are treated by the chemotherapy drugs, but these drugs have side effects and gastrointestinal toxicity is the most prevalent. one of the main roles of nurses is to better health through patient education and care for him. evidence-based nursing is a process during which the nurse can use the available research evidence, their c...

patients with acute myeloblastic leukemia (aml) with monosomy 7 are a group of patients with refractory aml who have a very poor prognosis. therefore, rationally designed new therapies, including metronomic chemotherapy regimen with histidine deacetylase inhibitors (valporic acid, atra) are being investigated as potential treatments for the population of refractory cases of aml. herein, we repo...

basal cell carcinoma (bcc) is the most common cancer among humans, and the standard treatment is surgery. other modalities are reserved as a second line of treatment. topical chemotherapy may be used in primary bcc. systemic chemotherapy has no role in the primary treatment of bcc, although it may be efficacious in metastatic cases. we report the case of a patient with persistent recurrent bcc ...

In order to evaluate the results of abdominal radiation plus chemotherapy in cases with stage II and III of immunoproliferative small intestinal disease in comparison to chemotherapy alone, fifty-one patients referred to Shiraz University of Medical Sciences' affiliated hospitals were studied between 1980 and 1994. Out of them 38 patients who had an abdominal mass were gathered into two gro...