BACKGROUND Image-guided (IG) intensity-modulated radiotherapy (IMRT) enables maximal tumor margin reduction for the sparing of organs at risk (OARs) when used to treat locally advanced non-small cell lung cancer (NSCLC) with definitive chemo-radiation. It also allows for the incorporation of stereotactic ablative radiotherapy (SABR) into the treatment regimen. Here, we describe our initial expe...

Heavy chain-binding protein (BiP) associates posttranslationally with nascent Ig heavy chains in the endoplasmic reticulum (ER) and remains associated with these heavy chains until they assemble with light chains. The heavy chain-BiP complex can be precipitated by antibody reagents against either component. To identify sites on heavy chain molecules that are important for association with BiP, ...

BACKGROUND Different serological tests are used in serologic diagnosis of brucellosis. The most widely used of these are Standard Tube Agglutination and Coombs anti-brucella tests. Whereas ELISA Ig M and Ig G tests have been in use for a long time, immuncapture agglutination test has been recently introduced and used in serological diagnosis. The aim of this study was to compare diagnostic valu...

OBJECTIVE This study was designed to evaluate vascular morphological and morphometric changes induced by brachytherapy with samarium-153 (Sm-153) at high doses in hypercholesterolemic rabbits. METHODS Forty-three New Zealand White hypercholesterolemic rabbits were analyzed, and the total of 86 iliac arteries underwent balloon angioplasty injury. The rabbits were divided into three different g...

In contrast to adult lymphocytes, neonatal lymphocytes secrete minimal amounts of Ig in response to stimulation with immobilized MAb to CD3. This deficiency could be overcome by the addition of supplemental IL-2, IL-4, or IL-6, resulting in the secretion of all Ig isotypes. There were no major differences in the distribution of Ig isotypes secreted in response to the cytokines alone or in combi...

We developed a flow cytometric method for the enumeration and classification of nonmalignant immature granulocytes (IG). In this study, IG are defined as most immature (IG stage 1: promyelocytes and myelocytes) and as more mature (IG stage 2: metamyelocytes). Blood specimens from 46 patients with documented infectious or inflammatory disease and known presence of IG (by routine manual microscop...

We examined the lg heavy chain variable region genes (Ig V(H) genes) expressed in biopsy specimens of 10 patients with acquired immunodeficiency syndrome (AIDS)-associated lymphoma. Eight expressed Ig V(H) genes of the V(H)4 group, indicating a bias toward expression of Ig V(H) genes of this subgroup. Sequence analyses of Ig V(H) genes isolated from any one lymphoma did not reveal evidence for ...

Background. Effective treatment of acute ischemic stroke requires reperfusion salvageable tissue. We investigated the predictors penumbra salvage (PS) and infarct growth (IG) in a large cohort patients. Methods. In ASTRAL registry from 2003 to 2016, we selected middle cerebral artery strokes <24 h with high-quality CT angiography perfusion. PS IG were correlated multivariate analyses clinica...

Nhiễm khuẩn huyết là một trong những nguyên nhân hàng đầu gây tử vong ở trẻ em. Chẩn đoán sớm nhiễm giúp giảm tỉ lệ vong, thời gian nằm viện và cải thiện tiên lượng của bệnh nhân. Mục tiêu nghiên cứu này nhằm xác định giá trị số chỉ bạch cầu hạt mở rộng chẩn Nghiên mô tả cắt ngang, hồi trên 3 nhóm gồm 120 huyết, 60 tại chỗ không từ tháng 2/2022 đến 2/2023. Số cầu, chưa trưởng thành (số IG#, IG%...