نتایج جستجو برای: ifn therapy
تعداد نتایج: 685719 فیلتر نتایج به سال:
PURPOSE This study was to determine the role of tumor-infiltrating macrophages in IFN-beta-induced host defense against prostate cancer. EXPERIMENTAL DESIGN Efficacy of adenovirus-mediated IFN-beta gene therapy against orthotopic xenografts of human prostate cancer was tested in macrophage-compromised nude mice. Immunohistochemistry and Northern blotting were used to elucidate mechanisms resp...
Treatment of nonhealing forms of human leishmaniasis with antimonial drugs in combination with gamma interferon (IFN-gamma) may promote healing more effectively than conventional drug therapy. Although the natures of immune responses in patients prior to treatment are often unclear, it is generally assumed that such therapy also promotes a switch from a Th2-type response to a dominant Th1-type ...
Treatment of chronic hepatitis C with Interferon (IFN) alpha2b monotherapy results in 10% to 15% sustained virological response (SVR). Combining IFN with ribavirin increases this response. In this analysis, using the Markov model, 6 treatment strategies for chronic hepatitis C (previously untreated) were compared on the basis of incremental cost per additional quality-adjusted life years ($/QAL...
BACKGROUND AND AIMS Chronic hepatitis C is a slowly progressive disease and eventually causes hepatocellular carcinoma in many patients. Although interferon (IFN) therapy has been used for viral eradication, its success rate is only about 30%. In patients in whom it has failed (non-responders), there are several patterns of serum alanine aminotransferase (ALT) values, and detection of serum HCV...
background previous studies using pegylated interferon (peg-ifn) and ribavirin (rbv) combination therapy suggested that patients with hepatitis c virus (hcv) genotype 1 and low pretreatment hcv rna level who achieved rapid virological response (rvr) can be treated for 24 weeks without compromising sustained virological response (svr) rate. objectives the current study aimed to investigate the e...
Interferon alpha (IFN-alpha) therapy is associated with a number of immunological side-effects, including autoimmune diseases and a 10% prevalence of thyroiditis. Hepatitis C virus (HCV) infection itself predisposes to autoimmune phenomena including hypothyroidism and myositis. The development of clinical hypothyroidism in the presence of positive thyroid antibodies in patients infected with HC...
Introduction. Interferons are produced in response to the presence of pathogens cells and responsible for proper formation immune reaction. Preliminary data obtained studies properties recombinant interferon gamma (IFN-γ) that involved patients with community-acquired pneumonia (including bacterial), acute respiratory viral infection (ARVI), influenza new coronavirus have shown promising result...
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