نتایج جستجو برای: ibandronate

تعداد نتایج: 387  

2010
Anita V Neutzsky-Wulff Mette G Sørensen Dino Kocijancic Diana J Leeming Morten H Dziegiel Morten A Karsdal Kim Henriksen

BACKGROUND Normal osteoclasts resorb bone by secretion of acid and proteases. Recent studies of patients with loss of function mutations affecting either of these processes have indicated a divergence in osteoclastic phenotypes. These difference in osteoclast phenotypes may directly or indirectly have secondary effects on bone remodeling, a process which is of importance for the pathogenesis of...

2015
Josep Darbà Lisette Kaskens Francesc Sorio Vilela Mickael Lothgren

BACKGROUND The objective of this study was to estimate the cost-effectiveness of denosumab for fracture prevention compared with no treatment, generic bisphosphonates, and strontium ranelate in a cohort of osteoporotic postmenopausal women in Spain. METHODS A Markov model represented the possible health state transitions of Spanish postmenopausal women from initiation of fracture prevention t...

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