OBJECTIVE Obesity increases morbidity and resource utilization in sepsis patients. Sepsis transitions from early/hyper-inflammatory to late/hypo-inflammatory phase. Majority of sepsis-mortality occurs during the late sepsis; no therapies exist to treat late sepsis. In lean mice, we have shown that sirtuins (SIRTs) modulate this transition. Here, we investigated the role of sirtuins, especially ...

BACKGROUND Severe malnutrition contributes up to 50% of childhood mortality in developing countries is frequently characterised by electrolyte depletion, including low total body phosphate. During therapeutic re-feeding, electrolyte shift from extracellular to intra-cellular compartments may induce hypo-phosphataemia (hypo-P) with resultant increased morbidity and mortality. This biochemical im...

A number of studies have reported that hypo-albuminaemia is powerful predictor of subsequent mortality in ESRF patients (Lowrie 1990, Owen 1993). The precise role of comorbidity, inflammatory/infective conditions and poor nutrition in the hypo-albuminaemia and the increased mortality rate is uncertain (Kaysen 1995). There are no prospective studies demonstrating a reduction in mortality followi...

In this paper we offer a formal account of reasoning with legal cases in terms of argumentation schemes. These schemes, and undercutting attacks associated with them, are formalised as defeasible rules of inference within the ASPIC+ framework. We begin by modelling the style of reasoning with cases developed by Aleven and Ashley in the CATO project, which describes cases using factors, and then...

We extend the applicability of idempotent methods to deterministic dynamic games through the min-max distributive property. This induces a very high curse-of-complexity. A representation of the space of max-plus hypo-convex functions as a min-max linear space is used to obtain a method for attenuating this complexity growth. This is applied in a game of search and deception. The problem is form...

In rodents, insufficient thyroid hormone (TH) gestationally has adverse effects on cerebral cortex development. Comparable studies of humans examining how TH insufficiency affects cortical morphology are limited to children with congenital hypothyroidism or offspring of hypothyroxinemic women; effects on cortex of children born to women with clinically diagnosed hypothyroidism are not known. We...

Original Article Blood pressure serum calcium level pregnancy

The aims of this study are twofold. We first seek to validate a previous study conducted on one speaker. It identified lower face visible articulatory correlates of contrastive focus in French for real (nonreiterant) speech. We thus conducted the same study for another speaker. Our second goal was to enlarge the set of cues measured to other facial movements. To do so we used a complementary me...