BACKGROUND Keloids and hypertrophic scars represent excessive scarring. They require different therapeutic approaches, which can be hampered because of an apparent lack of morphologic difference between the two diseases. OBJECTIVE This study investigated the clinical and dermoscopic features of keloids and hypertrophic scars in order to help dermatologists distinguish these lesions better. ...

In 2013, the Japan Gastroenterological Endoscopy Society introduced Kyoto classification of gastritis, which is useful to predict Helicobacter pylori infection based exclusively on endoscopic findings. Based gastric mucosal atrophy, intestinal metaplasia, hypertrophic folds, nodularity, and diffuse redness may be associated with cancer H. infection, are common findings in Koreans. Atrophy metap...

Cardiac adaptation to unremitting physiological stress typically involves hypertrophic growth of cardiomyocytes, a compensatory response that often fails and causes heart disease. Gene array analysis identified AKIP1 (A Kinase Interacting Protein 1) as a hypertrophic gene and we therefore hypothesized a potential role in the hypertrophic response. We show for the first time that both AKIP1 mRNA...

Keloids and hypertrophic scars are different expressions of the same derailment of wound healing; their biological behaviors and appearances are quite different. The clinical differences between hypertrophic scars and keloids have long been recognized. However, distinguishing between the two types of scars on histology is sometimes difficult as the ‘keloid collagen’, the hallmark of keloid, is ...

Hypertrophic burn scars pose a challenge for burn survivors and providers. In many cases, they can severely limit a burn survivor's level of function, including work and recreational activities. A widespread modality of prevention and treatment of hypertrophic scarring is the utilization of pressure garment therapy (PGT). Despite the magnitude of the problem of hypertrophic scarring and the ubi...

Inositol 1,4,5'-triphosphate receptor II (IP(3)RII) calcium channel expression is increased in both hypertrophic failing human myocardium and experimentally induced models of the disease. The ectopic calcium released from these receptors induces pro-hypertrophic gene expression and may promote arrhythmias. Here, we show that IP(3)RII expression was constitutively restrained by the muscle-specif...

structive hypertrophic cardiomyopathy. J Clin Invest 66: 1369, 1980 30. Stefadouros MA, Canedo MI, Karayannis E, Abdulla A, Frank MJ: Internally recorded systolic time intervals in hypertrophic subaortic stenosis. Am J Cardiol 40: 700, 1977 31. Nesje OA, Enge I: External carotid pulse recordings in hypertrophic obstructive cardiomyopathy. Acta Med Scand 202: 197, 1977 32. Henry WL, Clark CE, Gr...

Immunoglobulin G4 (IgG4)-related hypertrophic pachymeningitis, defined as focally or diffusely thickened dura mater and lymphoplasmacytic infiltration with increased IgG4 bearing plasma cells, is a rare disease. Moreover, cases involving bone are even rarer. In this report, the authors describe a case of IgG4-related hypertrophic pachymeningitis involving the skull in a 65-year-old man presenti...

BACKGROUND AND PURPOSE Posterior fossa syndrome is a severe postoperative complication occurring in up to 29% of children undergoing posterior fossa tumor resection; it is most likely caused by bilateral damage to the proximal efferent cerebellar pathways, whose fibers contribute to the Guillain-Mollaret triangle. When the triangle is disrupted, hypertrophic olivary degeneration develops. We hy...

Diabetes effects start in utero and affect neonates, infants, children and adolescent. Gestational diabetes may have overwhelming effects on the embryonic heart as well as the infants born to diabetic mothers. The neonates and infants suffering this metabolic disease may have considerable cardiovascular effects [1]. Hypertrophic cardiomyopathy is a well known condition observed in infants of di...