anti-androgens are an assorted group of drugs and compounds that reduce the levels or activity of androgen hormones within the human body. disease states in which this is relevant include polycystic ovarian syndrome, hirsutism, acne, benign prostatic hyperplasia, and endocrine related cancers such as carcinoma of the prostate. we provide an overview and discussion of the use of anti-androgen me...

labeo rohita fingerlings were reared in freshwater and exposed to different concentrations of lead nitrate. after the exposure, one fish was sacrificed from each dose and the gill arches were removed. the ultrastructural changes on the gills of this cyprinid fish were investigated through scanning electron microscope (sem). lead treated gill tissues showed certain marked changes such as uplifti...

Introduction: Papillary thyroid carcinoma (PTC) is the most common malignant neoplasm of neck. Most cases PTC are diagnosed based on pathologic criteria. However, few lesions that mimic nuclear features or architecture pose diagnostic problems. projections may be encountered in benign papillary hyperplasia multinodular goiter, Hashimoto’s thyroiditis, and Graves’ disease. For this reason, appro...

Penelitian ini merupakan penelitian eksperimental yang bertujuan mengetahui pengaruh umur ikan terhadap akumulasi logam Pb (NO3)2 dengan konsentrasi 25 ppm pada organ insang dan hati, gambaran histologi sintasan dilaksanakan selama 7 (tujuh) hari. Populasi digunakan adalah Nila (O. niloticus) berumur 1 bulan, 2 3 bulan. Sampel yaitu hati Hasil menunjukkan bahwa rata-rata nilai tertinggi perlaku...

PURPOSE Endometrial carcinoma (EC) is common in the population and the most frequent extracolonic malignancy in hereditary nonpolyposis colorectal carcinoma (HNPCC)/Lynch syndrome. We characterized precursor lesions of endometrioid EC to identify markers of malignant transformation and tumor progression. EXPERIMENTAL DESIGN Serial specimens of normal endometrium, simple hyperplasia, complex h...

white sponge nevus (wsn) is a rare hereditary dyskeratotic hyperplasia of mucous membranes. it is an autosomal dominant disorder with variable penetrance. we report a case of wsn in a healthy 21-year-old male with no history of familial involvement. a white smooth plaque with no erythema or other structural abnormalities was observed, which confirmed the diagnosis of wsn histopathologically.

introduction nonclassical congenital adrenal hyperplasia (cah) is characterized by sufficient cortisol and aldosterone production at the cost of androgen overproduction. hydrocortisone or dexamethasone in supraphysiological doses are current treatment; however, their downside is suppression of endogenous cortisol production resulting in corticosteroid dependency. we aimed to treat children with...

thirty cases of benign prostatic hyperplasia and 30 cases of prostatic adenocarcinoma were selected and stained by agnor (argyrophilic staining of the nucleolar organizer region) method. specimens were obtained by either prostatectomy (open!tijr) or needle biopsy of the prostate. in this study, the sections of prostatic adenocarcinoma were reviewed. 6 cases were diagnosed as well-differentiated...