To the Editor: Martin et al.1 described a meta-analysis of 17 randomized controlled trials evaluating renal function in 1,230 total surgical patients allocated to hydroxyethyl starch (HES) 130/0.4 or control fluid. At baseline, mean serum creatinine (SCr) was lower in HES 130/0.4 recipients than the control group, and after surgery, the most extreme mean SCr values were higher in the patients r...

BACKGROUND The fluid kinetics of intravenously infused colloid during inhalation anesthesia and hemorrhage have not been investigated. We therefore assessed fluid space changes during infusion of hydroxyethyl starch solution after hemorrhage in conscious and desflurane-anesthetized individuals. METHODS Following the donation of 400 ml of blood, 500 ml of hydroxyethyl starch solution was infus...