نتایج جستجو برای: hydrophobic copolymers

تعداد نتایج: 40976  

Journal: :Langmuir : the ACS journal of surfaces and colloids 2012
Jinming Hu Yinfeng Qian Xiaofeng Wang Tao Liu Shiyong Liu

We report on the fabrication of organic/inorganic hybrid micelles of amphiphilic block copolymers physically encapsulated with hydrophobic drugs within micellar cores and stably embedded with superparamagnetic iron oxide (SPIO) nanoparticles within hydrophilic coronas, which possess integrated functions of chemotherapeutic drug delivery and magnetic resonance (MR) imaging contrast enhancement. ...

Journal: :Biomacromolecules 2007
Eric D Pressly Raffaella Rossin Aviv Hagooly Ken-Ichi Fukukawa Benjamin W Messmore Michael J Welch Karen L Wooley Matthew S Lamm Rohan A Hule Darrin J Pochan Craig J Hawker

The synthesis of poly(methyl methacrylate-co-methacryloxysuccinimide-graft-poly(ethylene glycol)) (PMMA-co-PMASI-g-PEG) via living free radical polymerization provides a convenient route to well-defined amphiphilic graft copolymers having a controllable number of reactive functional groups, variable length PEG grafts, and low polydispersity. These copolymers were shown to form PMMA-core/PEG-she...

2015
Victor R. de la Rosa Werner M. Nau Richard Hoogenboom

A series of water insoluble poly[(2-ethyl-2-oxazoline)-ran-(2-nonyl-2-oxazoline)] amphiphilic copolymers was synthesized and their solubility properties in the presence of different supramolecular host molecules were investigated. The resulting polymer-cavitand assemblies exhibited a thermoresponsive behavior that could be modulated by variation of the copolymer composition and length. Interest...

2006
J. F. Tan L. Bromberg K. C. Tam H. P. Too T. A. Hatton

Our previous studies have demonstrated that surfaceactive copolymers of Pluronic® surfactants and tertiary amino polycations such as poly (2-dimethylaminoethyl methacrylate) (PDMA) possess an enhanced DNA transfection efficiency compared to PDMA homopolymers. In order to understand the mechanism of such action, we conducted model studies of the interaction of polymer with phospholipid vesicles ...

Journal: :Bioconjugate chemistry 2017
Renjie Liu Dharmesh Patel Hazel R C Screen C Remzi Becer

Electrospun biodegradable membranes have attracted great attention for a range of tissue engineering applications. Among them, poly(ε-caprolactone) (PCL) is one of the most widely used polymers, owing to its well-controlled biocompatibility and biodegradability. However, PCL also has a number of limitations, such as its hydrophobic nature and the lack of functional groups on its side chain, lim...

2016
Roberto Nisticò Giuliana Magnacca Sushilkumar A Jadhav Dominique Scalarone

Large-mesopore silica films with a narrow pore size distribution and high porosity have been obtained by a sol-gel reaction of a silicon oxide precursor (TEOS) and using polystyrene-block-poly(ethylene oxide) (PS-b-PEO) copolymers as templates in an acidic environment. PS-b-PEO copolymers with different molecular weight and composition have been studied in order to assess the effects of the blo...

Journal: :Biomacromolecules 2008
Ken-ichi Fukukawa Raffaella Rossin Aviv Hagooly Eric D Pressly Jasmine N Hunt Benjamin W Messmore Karen L Wooley Michael J Welch Craig J Hawker

The synthesis of core-shell star copolymers via living free radical polymerization provides a convenient route to three-dimensional nanostructures having a poly(ethylene glycol) outer shell, a hydrophilic inner shell bearing reactive functional groups, and a central hydrophobic core. By starting with well-defined linear diblock copolymers, the thickness of each layer, overall size/molecular wei...

Journal: :Journal of biomedical optics 2011
Mathieu Maurin Olivier Stéphan Jean-Claude Vial Seth R Marder Boudewijn van der Sanden

Our purpose is to test if Pluronic® fluorescent nanomicelles can be used for in vivo two-photon imaging of both the normal and the tumor vasculature. The nanomicelles were obtained after encapsulating a hydrophobic two-photon dye: di-stryl benzene derivative, in Pluronic block copolymers. Their performance with respect to imaging depth, blood plasma staining, and diffusion across the tumor vasc...

Journal: :Journal of controlled release : official journal of the Controlled Release Society 2004
Fariyal Ahmed Dennis E Discher

Controlled release polymer vesicles are prepared using hydrolysable diblock copolymers of polyethyleneglycol-poly-l-lactic acid (PEG-PLA) or polyethyleneglycol-polycaprolactone (PEG-PCL). Encapsulation studies with a common anti-cancer agent, doxorubicin, show loading comparable to liposomes. Rates of encapsulant release from the hydrolysable vesicles are accelerated with an increased proportio...

Journal: :Nanomanufacturing 2022

This work presents the utilization of amphiphilic poly(oligo(ethylene glycol) methyl methacrylate)-co-poly(2-(diisopropylamino)ethyl methacrylate), P(OEGMA-co-DIPAEMA), hyperbranched (HB) copolymers, forming polymeric aggregates in aqueous media, as building nanocomponents and nanocarriers for entrapment magnetic cobalt ferrite nanoparticles (CoFe2O4, MNPs), hydrophobic drug curcumin (CUR) thei...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید