Abstract Mixed micellar systems have been tried with the aim of achieving higher solubility drugs compared to single systems. Hydrophobic-hydrophilic mixed used for above purpose drug ciprofloxacin in past. In present study, a hydrophilic-hydrophilic binary system comprising pluronic copolymers F127 and L64 has studied its effect on solubilization Ciprofloxacin. The solutions two individual the...

the surface parameter of nanoparticles such as hydrophobicity and a hydrophilicity on protein structure and function is very important. in this study, conformational changes of glucose oxidase (gox) in the mercaptopurine: gnps and 11-mercaptoundecanoic acid: gnps as a hydrophobic and a hydrophilic gnps surface was investigated by various spectroscopic techniques, including: uv-vis absorption, f...

Hydrophilic interaction chromatography (HILIC) was first introduced by Alpert in 1990 [...]

aqueous (hydrophilic) and chloroform (lipophilic) extracts of nine medicinal plants currently used in traditional medicine, in egypt, to treat some gastrointestinal tract (git) disorders were tested for their gastro-protective effect against the incidence of peptic ulcer. indomethacin-induced ulcer in a rat model was used for this testing. mentha microphylla, brassica oleracea capitata (cabbage...

Quercetin is a bioflavonoid compound with low water solubility in both foods and the gastrointestinal tract, which limits exploitation of its health-promoting properties. This study aims to formulate solid dispersions (SDs) quercetin hydrophilic polyethylene glycol PEG matrices, using melt-mixing method, improve dissolution antioxidant activity quercetin. Initially, total Gibbs free energy for ...

A great challenge hindering the use of cellulose nanofibers (CNF) as a reinforcing filler in bio-based polymeric matrices are their poor chemical compatibility. This is because inherent hydrophilic nature CNF and hydrophobic matrix. In this study, laminates were prepared by using acetate butyrate (CAB) polymer To improve compatibility between CAB CNF, residual hydroxyl groups on surface cross-l...