QSAR/QSTR modelling constitutes an attractive approach to preliminary assessment of the impact on environmental health by a primary pollutant and the suite of transformation products that may be persistent in and toxic to the environment. The present paper studies the impact on environmental health by residuals of the rocket fuel 1,1-dimethyl hydrazine (heptyl) and its transformation products. ...

Intramolecular photoinduced electron transfer from a hydrazine unit to an aromatic group is studied by resonance Raman spectroscopy and electronic absorption spectroscopy. Substituted hydrazine functional groups have played an important role in studies of electron-transfer reactions, photoinduced intramolecular electron transfer, and of mixed valence. A prototypical compound, 2-tert-butyl-3-(an...

An amperometric sensor for hydrazine determination was developed using a surface modified copper (II) hexacyanoferrate (CuHCF) nanoparticles carbon ceramic composite electrode (CCE) by a versatile sol-gel technique using aminopropyl trimethoxy silane (APTMOS). The characterization of the modified electrode has been carried out by electrochemical techniques such as cyclic voltammetry, hydrodynam...

The prophage-inducing capability of hydroxylamine sulfate and 36 of its derivatives, and of hydrazine dihydrochloride and dihydrazine sulfate and 43 of their derivatives, was determined in Escherichia coli W1709 (lambda). Maximal nontoxic concentrations up to 1 mg/ml were tested. Hydroxylamine sulfate was active at 2.5 mug/ml and the following 17 derivatives were active at concentrations rangin...

A series of 1-(N-substituted-1H-indol-3-yl)-3-arylprop-2-ene-1-ones (2a, b-4a, b) were prepared and allowed to react with urea, thiourea or guanidine to give pyrimidine derivatives 5a, b-13a, b. Reaction of 2a, b-4a, b with ethyl acetoacetate in the presence of a base gave cyclohexanone derivatives 14a, b-16a, b. Reaction of the latter compounds with hydrazine hydrate afforded indazole derivati...

In this work, a simple electrochemical immunoassay based on platinum nanoparticles (PtNPs) using open circuit potential (OCP) detection was developed. The detection of human chorionic gonadotropin hormone (hCG) as a model analyte, was demonstrated by direct electrical detection of PtNPs in hydrazine solution using OCP measurement without any application of either potential or current to the sys...

Owing to their present use as rocket fuels and their pharmacologic activity as central nervous system stimulants, substituted hydrazines and hydrazine derivatives have come into increasing use in recent years. The parent compound hydrazine and the methyl-substituted hydrazines are of potential hazard because of their toxicity, volatility, and explosive nature. Exposure to hydrazine vapor brings...

Treatment of 2,3-diaryloxirane-2,3-dicarbonitriles 1a-c with different nitrogen nucleophiles, e.g., hydrazine, methyl hydrazine, phenyl hydrazine, hydroxylamine, thiosemicarbazide, and/or 2-amino-5-phenyl-1,3,4-thiadiazole, afforded pyrazole, isoxazole, pyrrolotriazine, imidazolothiadiazole derivatives 2-5, respectively. Reacting pyrazoles 2a-c with aromatic aldehydes and/or methyl glycinate pr...