نتایج جستجو برای: human immune

تعداد نتایج: 1841585  

SARS-CoV-2 is a novel strain of the coronaviruses posing great challenges to the human immune system. Hence, human innate immunity determines how our body responses to the early infection (1-3). According to the studies, coronavirus can cause a range of symptoms by affecting various organs in the body (4, 5). Currently, our hospital is one of the referral centers of COVID-19 in Iran. We would l...

Akbar Vahdati Edna Abkar Minoo Adib, Shirin Kashfi, Taji Afrooz

Background: Erythropoietin (EPO) was first known as a factor for red blood cell proliferation and differentiation. New studies show the effects of EPO on immune system. Objective: In this study, the effects of pretreatment with recombinant human erythropoietin (rHuEPO) on the anti-human leukocyte antibody (anti-HLA) titer were determined. Methods: Three groups of rats were sensitized with human...

Journal: :iranian journal of immunology 0
akbar vahdati biology department, faculty of sciences, isfahan university, isfahan minoo adib immunology department, faculty of medicine, isfahan university of medical sciences, isfahan, shirin kashfi biology department, faculty of sciences, isfahan university, isfahan taji afrooz biology department, faculty of sciences, isfahan university, isfahan edna abkar immunogenetics lab., ali asghar hospital, isfahan, iran

background: erythropoietin (epo) was first known as a factor for red blood cell proliferation and differentiation. new studies show the effects of epo on immune system. objective: in this study, the effects of pretreatment with recombinant human erythropoietin (rhuepo) on the anti-human leukocyte antibody (anti-hla) titer were determined. methods: three groups of rats were sensitized with human...

Journal: :Blood 2015
Jeremy A Goettel Subhabrata Biswas Willem S Lexmond Ada Yeste Laura Passerini Bonny Patel Siyoung Yang Jiusong Sun Jodie Ouahed Dror S Shouval Katelyn J McCann Bruce H Horwitz Diane Mathis Edgar L Milford Luigi D Notarangelo Maria-Grazia Roncarolo Edda Fiebiger Wayne A Marasco Rosa Bacchetta Francisco J Quintana Sung-Yun Pai Christoph Klein Aleixo M Muise Scott B Snapper

Mice reconstituted with a human immune system provide a tractable in vivo model to assess human immune cell function. To date, reconstitution of murine strains with human hematopoietic stem cells (HSCs) from patients with monogenic immune disorders have not been reported. One obstacle precluding the development of immune-disease specific "humanized" mice is that optimal adaptive immune response...

Dear Editor, Cigarette smoking has destructive effect on periodontal tissue. The rates of loss of periodontal attachment and recession of gingival are higher in smokers than non-smokers (1-2). Previous studies on the inflammatory immune responses in smokers’ periodontitis have mainly focused on the role of neutrophils. Tumor necrosis factor–α, prostaglandin E2 and matrix metalloproteinase...

Journal: Vaccine Research 2015
A Ataei- Pirkooh , F Goudarzifar , H Keyvani , M Eslami, MR Aghasadeghi , R Vahabpour , SH Monavari ,

Introduction: Glycoprotein B (gB) is the major antigen for induction of humoral responses against human cytomegalovirus (HCMV) making it an attractive candidate for immune prophylaxis. In the present study, the humoral immune response of BALB/c mice to a truncated HCMV gB protein fused with GFP was evaluated. Methods: The truncated gB coding sequence was synthesized and cloned in pEGFPN1 eukary...

Journal: :iranian journal of virology 0
z azarkar assistant professor of infectious disease, birjand university of medical sciences, birjand, iran

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Journal: :Journal of Dairy, Veterinary & Animal Research 2023

A main reason for veterinary consultation is related to dermatological conditions, with pruritus as a frequent complaint. Allergic-based Inflammatory conditions several complications, such alopecia and secondary infections, are common. Besides the immune-mediated triggering factors, assessment of skin barrier, aiming restoring its effect stands essential. Defects in lipid protein constitution a...

Journal: :Blood 2006
Ping Lan Noriko Tonomura Akira Shimizu Shumei Wang Yong-Guang Yang

Studies of the human immune system have been limited by the lack of an appropriate in vivo model. For this reason, efforts have been made to develop murine models with a functional human immune system. We report here that cotransplantation of human fetal thymus/liver tissues and CD34(+) hematopoietic stem/progenitor cells led to the development of sustained human hematopoiesis and a functional ...

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