Amelogenesis imperfecta (AI) is a heterogeneous group of genetic conditions that result in defective dental enamel formation. Amelotin (AMTN) is a secreted protein thought to act as a promoter of matrix mineralization in the final stage of enamel development, and is strongly expressed, almost exclusively, in maturation stage ameloblasts. Amtn overexpression and Amtn knockout mouse models have d...

AIM To analyse the anti-caries properties of nicomethanol hydrofluoride (NH) and the benefit of its combination with siliglycol, a coating agent. METHODS Fluoride (F) uptake by dental enamel and synthetic apatite treated with NH was measured in vitro and compared to treatment with mineral fluorides. The addition of siliglycol was also tested. The effect of NH (as a mouthwash) on salivary pH w...

Cross-sectional study of sound primary dental enamel revealed hardness zonation and, in parallel, significant change the Mg content below prismless layer. is known to play an important role apatite biomineralization, therefore, ion exchange experiments were carried out on outer surface molars and reference abiogenic Ca-phosphates using MgCl2 solution. Effects incorporation crystal/particle size...

There are two objectives. One is to show the differences in the mechanical properties of various dental restorative materials compared to those of enamel and dentin. The other is to ascertain which dental restorative materials are more suitable for clinical treatments. Amalgam, dental ceramic, gold alloy, dental resin, zirconia, and titanium alloy were processed as dental restorative material s...

GOALS AND BACKGROUND European studies have demonstrated that dental enamel defects and oral aphthae are observed in celiac disease (CD). We investigated this association in a US population. STUDY Biopsy proven CD patients and controls were recruited from a private dental practice and from CD support meetings. History of aphthae was taken and dental examination was performed by a single dentis...

The in vitro fluoride uptake by dental enamel from two conventional acidulated phosphate fluoride gels was compared to a thixotropic acidulated phosphate fluoride gel. The fluoride concentration and enamel biopsy depths were determined using an acid-etch biopsy method based on calcium determinations. A significant fluoride uptake by dental enamel from a thixotropic topical fluoride agent follow...

Background: Dairy products were recognised in the late 1950s as food group exhibiting most anticaries activities. Yogurt, a dairy product, almost as commonly consumed as milk has been subjected to less research in the context of its effect on oral health, especially on dental enamel. AIM: To compare invitro the effectiveness of probiotic enriched yogurt extract and traditional yogurt extract in...

The enamel knot, a transient epithelial structure, appears at the onset of mammalian tooth shape development. Until now, the morphological, cellular and molecular events leading to the formation and disappearance of the enamel knot have not been described. Here we report that the cessation of cell proliferation in the enamel knot in mouse molar teeth is linked with the expression of the cyclin-...

Discrete dental traits are used as proxies for biological relatedness among modern human populations and for alpha taxonomy and phylogeny reconstruction within the hominin clade. We present a comparison of the expression of lower molar dental traits (cusp 6, cusp 7, trigonid crest pattern, and protostylid) at the enamel-dentine junction (EDJ) in a variety of extant and fossil hominoid taxa, in ...