نتایج جستجو برای: human adipocyte

تعداد نتایج: 1648450  

Journal: :Archives of Cardiovascular Diseases Supplements 2016

Journal: :basic and clinical cancer research 0
seied rasoul razavi babaheidari blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran kamran mousavi hosseini blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran amir atashi department of hematology, school of medical sciences, tarbiat modares university, tehran, iran arezou oodi blood transfusion research center, high institute for research and education in transfusion medicine, tehran, iran shadi esmaeili department of hematology, school of medical sciences, tarbiat modares university, tehran, iran

background : many types of cancer cells require a supply of fatty acids (fa) for growth and survival, lpl, in the presence of triglyceride-rich lipoproteins, accelerates the growth of these cells. recent evidence shows that lpl plays important roles in inflammation and obesity, implies that it is an appropriate general target for chemo preventive and chemotherapeutic agents. thus, we reported l...

2011
Alessandra Rigamonti Kristen Brennand Frank Lau Chad A. Cowan

It was recently shown that cellular turnover occurs within the human adipocyte population. Through three independent experimental approaches--dilution of an inducible histone 2B-green fluorescent protein (H2BGFP), labeling with the cell cycle marker Ki67 and incorporation of BrdU--we characterized the degree of cellular turnover in murine adipose tissue. We observed rapid turnover of the adipoc...

2015
Mark P. Jedrychowski Libin Liu Collette J. Laflamme Kalypso Karastergiou Tova Meshulam Shi-Ying Ding Yuanyuan Wu Mi-Jeong Lee Steven P. Gygi Susan K. Fried Paul F. Pilch

OBJECTIVE Adipocytes are robust protein secretors, most notably of adipokines, hormone-like polypeptides, which act in an endocrine and paracrine fashion to affect numerous physiological processes such as energy balance and insulin sensitivity. To understand how such proteins are assembled for secretion we describe the function of a novel endoplasmic reticulum oxidoreductase, adiporedoxin (Adrx...

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