High spatial resolution (HSR) imagery and high density LiDAR data provide complementary horizontal and vertical information. Therefore, many studies have focused on fusing the two for mapping geographic features. It has been demonstrated that the synergetic use of LiDAR and HSR imagery greatly improves classification accuracy. This is especially true with waveform LiDAR data since they provide ...

The heat shock response (HSR) is essential for proteostasis and cellular health. In metazoans, aging is associated with a decline in quality control, thus increasing the risk for protein conformational disease. Here, we show that in C. elegans, the HSR declines precipitously over a 4 hr period in early adulthood coincident with the onset of reproductive maturity. Repression of the HSR occurs du...

In this study, a fair comparison of human and machine speech recognition is established by using the same paradigms for human speech recognition (HSR) and automatic speech recognition (ASR). In order to ensure equal conditions, a speech database specifically designed for this task is used. The results for HSR and ASR are broken down into several intrinsic variabilities like speaking rate, speak...

BACKGROUND In the last few decades, health systems research (HSR) has garnered much attention with a rapid increase in the related literature. This study aims to review and evaluate the global progress in HSR and assess the current quantitative trends. METHODS Based on data from the Web of Science database, scientometric methods and knowledge visualization techniques were applied to evaluate ...

ii Preface VA's Health Services Research and Development Service (HSR&D) works to improve the cost, quality, and outcomes of health care for our nation's veterans. Collaborating with VA leaders, managers, and policy makers, HSR&D focuses on important health care topics that are likely to have significant impact on quality improvement efforts. One significant collaborative effort is HSR&D's Evid...

Accumulation of misfolded protein in the endoplasmic reticulum (ER) causes stress. The unfolded protein response (UPR), a transcriptional induction pathway, is activated to relieve ER stress. Although UPR is not essential for viability, UPR-deficient cells are more sensitive to ER stress; ire1Delta cells cannot grow when challenged with tunicamycin or by overexpression of misfolded CPY(*). In t...

Following the calculation of optimal energy transfer in thermal environment in our first paper [J. L. Wu, F. Liu, Y. Shen, J. S. Cao, and R. J. Silbey, New J. Phys. 12, 105012 (2010)], full quantum dynamics and leading-order "classical" hopping kinetics are compared in the seven-site Fenna-Matthews-Olson (FMO) protein complex. The difference between these two dynamic descriptions is due to high...

PREFACE Health Services Research & Development Service's (HSR&D) Evidence-based Synthesis Program (ESP) was established to provide timely and accurate syntheses of targeted healthcare topics of particular importance to Veterans Affairs (VA) managers and policymakers, as they work to improve the health and healthcare of Veterans. The ESP disseminates these reports throughout the VA. HSR&D provid...

In this paper, we illustrate the close parallels between the research fields of human speech recognition (HSR) and automatic speech recognition (ASR) using a computational model of human word recognition, SpeM, which was built using techniques from ASR. We show that ASR has proven to be useful for improving models of HSR by relieving them of some of their shortcomings. However, in order to buil...

The story of AHCPR's struggle with Congress to remain a federal agency is an example of the longer struggle health services research (HSR) has had to hold a priority in the federal budget. But from another perspective, the growth of HSR has been substantial, albeit an up-and-down experience. Its survival during the turbulent years of 1995-1996 is attributed to a fundamental restructuring of its...