This report summarises the findings of a follow-up study to the HSE/DETR/Home Office/HM Treasury Project 'relativities' study (HSE CRR 273/2000), which sought to elicit public preferences for preventing fatalities in several hazard contexts (railway/road accidents and public/home fires). The very public debate in the media and elsewhere regarding the organisation of rail safety following the La...

In Japan, herpes simplex encephalitis (HSE) has historically been fatal in approximately 30% of all reported cases. After the induction of acyclovir (ACV), however, the mortality rate has decreased to 7.1% (1), and HSE is now regarded as a treatable disease. However, the rate of poor outcome including moderate or severe sequelae still remains at 30-40% of HSE patients, despite standard ACV trea...

By the time on first exploration of reservoirs and design refineries, there are many challenges appeared health, safety, environment (HSE) by conduction fossil fuels such as higher contents sulfur, nitrogen, oxygen, halogen, metals, aromatics. There side effects human health starting from simple to malignant diseases cancer. Also, safety equipement catalysts affected presence high content these...

BACKGROUND Information is needed at all stages of the policy making process. The Health Survey for England (HSE) is an annual cross-sectional health examination survey of the non-institutionalised general population in England. It was originally set up to inform national policy making and monitoring by the Department of Health. This paper examines how the nurse collected physical and biological...

BACKGROUND Tuberculous meningitis (TBM) and herpes simplex encephalitis (HSE) are common neurological diseases involving the brain parenchyma, and both can result in chronic epilepsy. Here, we identified possible variables affecting the prognosis of central nervous system (CNS) infection-related epilepsy. METHODS The clinical seizure characteristics and demographic data of 20 TBM- and 55 HSE-...

BACKGROUND This study presents a framework for development of integrated health, safety and ergonomic (HSE) in complex critical systems. Total ergonomics model considers conventional ergonomics factors as well as management and organizational factors. METHODS Control room operation and maintenance department of a thermal power plant was chosen as the case of our study. To achieve the above ob...

The Control of Substances Hazardous to Health Regulations 1994 (COSHH), provide the main British legislation to protect against health risks arising from hazardous substances used at work. Under the regulations, employers have a duty to carry out a suitable and sufficient risk assessment and take steps to ensure exposure is adequately controlled. The paper by Topping et al. (1998) concluded tha...

Proinflammatory cytokines, including IL-1beta and tumor necrosis factor-alpha (TNF-alpha), promote cancer cell adhesion and liver metastases by up-regulating the expression of vascular cell adhesion molecule-1 (VCAM-1) on hepatic sinusoidal endothelium (HSE). In this study, hepatic metastasis after intrasplenically injected mouse B16 melanoma (B16M) cells was reduced 84-95% in mice with null mu...

Chromopeptide siderophores (azotobactin 87-I and -II) were isolated from an iron deficient culture medium of Azotobacter vinelandii ATCC 12837 (= DSM 87). Their structures were elucidated by chemical degradation studies and spectroscopic methods, especially 2D-NMR-techniques. Total assignments of 1H-, 13C-, and 15N-resonances based on 2D-HOHAHA-, 1H/13C-HMQC-, 1H/13C-HMBC-, 1H/15N-HMQC/TOCSY-, ...

OBJECTIVE To determine the presence and kinetics of antibodies against synaptic proteins in patients with herpes simplex virus encephalitis (HSE). METHODS Retrospective analysis of 44 patients with polymerase chain reaction-proven HSE for the presence of a large panel of onconeuronal and synaptic receptor antibodies. The effect of patients' serum was studied in cultures of primary mouse hippo...