Objective: IR is a pathological condition strongly associated with obesity and involved in the pathogenesis of T2D. The treatment insulin resistant children firstly targeted to lifestyle interventions. Homeostasis model assessment resistance (HOMA-IR) may be useful for early evaluation teenagers could have long-term benefit preventive diagnostic therapeutic intervention. Method: A cross-section...

The aim of this study was to investigate the influence of rice bran oil consumption on plasma lipids and insulin resistance in patients with type 2 diabetes. Thirty-five patients with type 2 diabetes were randomly assigned to a placebo group or a rice bran oil group. The placebo group consumed 250 mL soybean oil-modified milk (18 g soybean oil) daily for 5 weeks, and the rice bran oil group con...

Adiposity and insulin resistance are closely associated with hypertension. This study aims to investigate whether the association between adiposity and hypertension is modified by insulin resistance. The cohort consisted of 1624 middle-aged normotensive black and white adults aged 18 to 43 years at baseline who followed for 16 years on average. Overweight/obesity at baseline was defined as body...

The effects of Ahmadi continuous nursing model in children with diabetic ketoacidosis were investigated this study. A total 120 (DKA) enrolled by convenience sampling from May 2018 to February 2022. Patients equally divided into a control group and an observation random number table. received the routine model, while additionally model. indicators clinical first aid, level blood glucose, insuli...

Iron is a transition metal capable of catalyzing redox reactions by generating free radicals. These free radicals generated damage cells by attacking cell membranes, proteins and deoxyribonucleic acids. This damage can occur in the beta cells of the pancreas leading to reduced insulin secretion and increased insulin resistance leading ultimately to abnormal glucose homeostasis and diabetes mell...

Background: Diabetes and obesity are associated with an increased risk of cardiovascular disease. Irisin is a newly recognized peptidic myokine with anti-obesity and anti-diabetic properties. This study aims to investigate the relationship between serum irisin levels with cardiometabolic biomarkers in patients with type 2 diabetes mellitus (T2DM). Methods: In this comparative cross- sectional s...

objective: dyslipidemia and insulin resistance (ir), occurring in most infertile women with polycystic ovarian syndrome (pcos), increase the risk of cardiovascular disease (cvd) and type 2 diabetes. this study aimed to assess the relationships between lipoprotein ratios and ir in pcos women. materials and methods: thirty six infertile women with pcos selected based on androgen excess society (a...

BACKGROUND Adipocyte-fatty acid binding protein (A-FABP), a major cytoplasmic protein in adipocytes, plays a central role in the development of diabetes and atherosclerotic cardiovascular disease in experimental animals. We have previously shown that A-FABP is present in the bloodstream and that its circulating levels correlate with metabolic risk factors in a cross-sectional study. In the pres...

Insulin resistance refers to the reduction in insulinmediated glucose uptake in insulin-sensitive tissues, specifically in skeletal muscle. As a compensatory response, hyperinsulinemia ensues to maintain normal blood glucose levels. In epidemiological studies, fasting insulin level is commonly used as a surrogate marker of insulin resistance. In normoglycemic subjects, fasting insulin correlate...

Insulin resistance refers to the reduction in insulinmediated glucose uptake in insulin-sensitive tissues, specifically in skeletal muscle. As a compensatory response, hyperinsulinemia ensues to maintain normal blood glucose levels. In epidemiological studies, fasting insulin level is commonly used as a surrogate marker of insulin resistance. In normoglycemic subjects, fasting insulin correlate...