University of Manitoba, Canada We have recently completed construction of a high resolution small animal PET insert designed for operation inside a Bruker 7T MRI. The PET insert is designed to achieve a 1 mm spatial resolution in the centre of its field of view (FOV) and fit within the 114 mm inner diameter of the Bruker BGA-12S gradient coil while accommodating the Bruker 35 mm volume RF coil ...

This contribution proposes a new temporal PET camera concept yielding a precise spatio-temporal localization of a scintillation event within a monolithic scintillator. This concept is promising for PET imaging. The key idea behind this concept is the ability of the system to accurately localize the region of detected un-scattered photons on the Si-PMT detector plane. Then, by ray tracing, an ac...

Positron emission tomography (PET) imaging is based on detecting two time-coincident high-energy photons from the emission of a positron-emitting radioisotope. The physics of the emission, and the detection of the coincident photons, give PET imaging unique capabilities for both very high sensitivity and accurate estimation of the in vivo concentration of the radiotracer. PET imaging has been w...

Before the advent of tomographic imaging, it was postulated that decay of (90) Y to the 0(+) excited state of (90)Zr may result in emission of a positron-electron pair. While the branching ratio for pair-production is small (~32 × 10(-6)), PET has been successfully used to image (90) Y in numerous recent patients and phantom studies. (90) Y PET imaging has been performed on a variety of PET/CT ...

PURPOSE In order to measure spatial resolution of a PET tomograph in clinical conditions, this study describes and validates a method based on the recovery coefficient, a factor required to compensate underestimation in measured radioactivity concentration for small structures. METHODS In a PET image, the recovery factors of radioactive spheres were measured and their comparison with simulate...

During the last decade increasingly sophisticated positron emission tomography (PET) scanners have been developed for imaging small laboratory animals. These systems often exhibit performance characteristics, e.g. spatial resolution, substantially better than contemporary human PET scanners and are often the first systems to demonstrate new technologies, e.g. avalanche photodiodebased detector ...

The aim of this study is to evaluate the impact of a high resolution (HR) image reconstruction with a voxel size of 2mm in comparison to the most routinely used standard reconstruction with 4mm voxels in patients suffering from prostate cancer having undergone (18)F-methylcholine PET/CT. Phantom studies were performed using a Jaszczak phantom and a custom made phantom containing small hot lesio...

UNLABELLED The purpose of this study was to compare optimized whole-body (WB) and dedicated high-resolution contrast-enhanced PET/CT protocols and contrast enhanced CT in the preoperative staging of primary squamous cell carcinoma of the head and neck. METHODS A total of 44 patients with clinically M0 squamous cell carcinoma of the head and neck underwent primary tumor resection and neck diss...

Abstract Background Q.Clear is a Bayesian penalized likelihood (BPL) reconstruction algorithm that presents improvements in signal-to-noise ratio (SNR) clinical positron emission tomography (PET) scans. Brain studies research require provides good spatial resolution and accentuates contrast features however, filtered back-projection (FBP) not available on GE SIGNA PET-Magnetic Resonance (PET-MR...