Three-dimensional (3D) tissue culture provides a physiologically relevant microenvironment for distinguishing malignant from non-malignant breast cell phenotypes. 3D culture assays can also be used to test novel cancer therapies and predict a differential response to radiation between normal and malignant cells in vivo. However, biological measurements in such complex models are difficult to qu...

As a key department within a healthcare organisation, the operating room is a hazardous environment, where the consequences of errors are high, despite the relatively low rates of occurrence. Team performance in surgery is increasingly being considered crucial for a culture of safety. The aim of this study was to describe team communication and the ways it fostered or threatened safety culture ...

in recent years, underactuated nonlinear dynamic systems trajectory tracking, such as space robots and manipulators with structural flexibility, has become a major field of interest due to the complexity and high computational load of these systems. hierarchical sliding mode control has been investigated recently for these systems; however, the instability phenomena will possibly occur, especia...

Purpose Supply chain integration (SCI) has become a key strategy for hotels in facing their environment. The purpose of this study is to analyze the effects organizational culture on three dimensions SCI. competing value framework divides into four types, namely, hierarchical, group, rational and developmental cultures. Design/methodology/approach A structural equations model was developed test...

The hierarchical hub location problem is encountered three-level network that is applied in production-distribution system, education system, emergency medical services, telecommunication network, etc. This paper addresses the hierarchical hub covering problem with single assignment accounting for mandatory dispersion of central hubs restriction as a special case. This formulation with incorpor...