Amino acid-derived propargylic amides are cyclised in a one-pot, Au(III)-catalysed operation to yield 5-bromomethyl oxazoles. These compounds are further elaborated to bis-heterocycles, dipeptide mimics and more.

Rh(II)-catalyzed novel tandem intramolecular cycloisomerizations of aldehydes or ketones with 1-sulfonyl 1,2,3-triazoles have been disclosed, providing a facile protocol to access a series of functionalized aza-bridged benzodioxepine heterocycles.

Prins cyclization of homoallylic alcohols, thiols, and amines with various aldehydes in an ionic liquid HF salt (Et(4)NF.5HF) afforded the corresponding 4-fluorinated heterocycles in excellent yields.

Methods for regioselective N-methylation and -alkylation of unsaturated heterocycles with “off the shelf” reagents are highly sought-after. This reaction could drastically simplify synthesis privileged bioactive molecules. Here we report engineered natural methyltransferases challenging N-(m)ethylation heterocycles, including benzimidazoles, benzotriazoles, imidazoles indazoles. The reactions p...

Nitrogen-rich heterocycles are essential for designing novel energetic green materials with the combination of high explosive performance and acceptable mechanical sensitivities.

One or more nitrogen-containing molecules constitute an important class of heterocyclic compounds in organic synthesis, due to their reactivity and presence many natural, human plant origin. These nitrogenous heterocycles play essential role various scientific domains, whether they are chemical, biological pharmacological. N-heterocycles the privileged source research topics developed by severa...

This review focuses on the heavier group 13–15 element-containing heterocycles of [4 n +2]-electron systems featuring classical and advanced aromatics.

The photoelectron (PE) spectra of 2,2'-bipyridine 1, 2 ,2 ' :6 ' ,2"-terpyridine 2, and 2,2 ' ,2" ,2" / tetrapyridine 3 have been measured using H e I radiation. For 1 — 3 standard SCF LCAO MO calculations wer also performed. Comparison of P E spectra and these calculations allowed the assignment o f Ti-ionizations and indirectly also the nitrogen lone pair ionizations in 1 — 3. Factors influen...