A number of methods have been employed in attempts to induce encephalitis in guinea pigs with the Levaditi C strain of herpes virus. Some of these consisted of different modes of inoculation of the virus itself and others of different ways of combining it with vesicular stomatitis and neurovaccine viruses so as to obtain the concomitant effects of both. In still another test the Levaditi virus ...

Pain associated with herpes zoster arise from the virul neuritis of the suffered trigeminal or spinal dorsal ganglion. Prolonged neuritis makes an irreversible nerve injury and continuous pain impulse develops a central sensitization. A post-herpetic neuralgia is thought to be a neuropathic pain due to the irreversible nerve injury and sensitization. It is important to treat herpetic pain compl...

Stromal herpetic keratitis has a poor prognosis. To date, corticosteroids appear to be the most efficatious agents against the condition. However, corticosteroids are immuno6uppresive, and may cause recurrences. The recent findings of decreased cellular immunity in the condition offer the possibility of using levamisole as the therapeutic agent. The present investigation was undertaken to evalu...

the histopathological findings include as following: gliosis (52%), neuronal necrosis (37%), perivascular cuffing (5.4%), hyperemia and hemorrhage in cerebral tissues (32.9%), hyperemia and hemorrhage in meninge(19.2%), prevascullar and preneuronal edema (52%), meningial edema (16.4%), vacuole in neurons (2.7%), vacuoleinneuropil( 8.2% ),protozoal cyct(5.4%). frequency of fetal brain lesions co...

purpose : to report an atypical case of acanthamoeba keratitis. patients & methods : a 19-year-old girl presented with a history of recurrent herpetic keratitis and a history of short-time contact lens wear. laboratory work-up for herpetic, bacterial, and acanthamoeba sources were negative and the patient failied to follow up. on later presentation she had corneal necrotizing stromal ulcer need...

Of 91 patients with genital ulceration, herpes simplex virus was isolated from 52 (57%) and Haemophilus ducreyi from 12 (13%); none had syphilis. The difference in incidence of other aerobes in patients and controls was not significant. Anaerobes, predominantly Bacteroides spp, were isolated from a large proportion (77%) of men and women patients with ulcers but from few control men. The most c...

The incidence of complicated herpes simplex keratitis appears to have increased and the important factor seems to be associated with the use of topical corticosteroid hormone. A good experimental model exists for the study of herpetic keratitis. The disease corresponds to the primary infection in man. The unfavorable effects of corticosteroid hormone on experimental herpetic keratitis is reported.