Seminal vesicle malformations are a rare cause of obstructive azoospermia, often associated with other internal genitalia and upper urinary tract birth defects. We report 5 new cases of seminal vesicle agenesis in men presenting with hypospermia and azoospermia. Imaging showed seminal vesicle unilateral agenesis in all patients. The remaining seminal vesicle was hypoplastic in 3 cases, dilated ...

Agenesis of the lung is not an uncommon anomaly, and when it is an isolated finding, it is compatible with even normal life (Hochberg & Naclerio 1955; Netterville 1957; Van Loon & Diamond 1962; Shenoy 1979). Hundreds of cases were reported in the world literature (Oyama et al. 1953; Valle 1955; Booth & Berry 1967; Maltz & Nadas 1968; Borja et al. 1970). Various associated malformations are comm...

Seminal vesicle cysts are rare and usually associated with ipsilateral renal agenesis. The diagnosis of seminal vesicle cysts may be delayed or missed because of the non-specific symptoms of this condition. In this study, we aimed to discuss the diagnosis and treatment of a left seminal vesicle cyst that was associated ipsilateral agenesis in a 24-year-old patient who presented to our outpatien...

The study of the possible genetic causes complex genital malformations is a subject great interest both to know its etiology and diagnosis for best reproductive advice in these patients. Recently, Chen et al. (1Chen N. Zhao S. Jolly A. Wang L. Pan H. Yuan J. al.Perturbations genes essential Müllerian duct Wölffian development Mayer-Rokitansky-Küster-Hauser syndrome.Am J Hum Genet. 2021; 108: 1-...

Seminal vesicle cysts associated with ectopic ureter and renal agenesis is a rare condition. We report on a 23-year-old man with a history of pelvic discomfort and post-coital testicular pain. The investigation disclosed a left seminal vesicle cyst, and an absent left kidney. The patient was successful submitted to resection of the left seminal vesicle, ureter, and dysplastic renal tissue altog...

The FRAS1-related extracellular matrix 1 (FREM1) gene encodes an extracellular matrix protein that plays a critical role in the development of multiple organ systems. In humans, recessive mutations in FREM1 cause eye defects, congenital diaphragmatic hernia, renal anomalies and anorectal malformations including anteriorly placed anus. A similar constellation of findings-microphthalmia, cryptoph...

BACKGROUND HWW syndrome is a very rare congenital anomaly of urogenital tract involving Mullerian ducts and mesonephric ducts. It is characterised by a triad of symptoms - uterus didelphys, obstructed hemivagina and ipsilateral renal agenesis. It can be classified based on a completely or incompletely obstructed hemivagina. It presents soon after menarche or shows delayed presentation depending...

A 12-year-old boy presented to the clinic of ophthalmology because of watering and discharge from his left lower eyelid. The inspection examination revealed an orifice that was associated with congenital lacrimal fistula (CLF). He underwent a complete ophthalmologic and systemic evaluation to explore possible associated findings. Systemic evaluation revealed multiple renal anomalies: right rena...