Oral dosage forms with adjustable drug release profiles were prepared using progesterone (PGR) as a poorly-soluble model drug. The made stack assemblies of functional modules. modules PGR-carrying HPMC films cut into wafer-like circular pieces. Two types used in the study; one exhibited comparatively fast and other slow release. vs. each type film utilized resulted from grade case. Drug loading...

Dissolution testing of the drug formulation introduced in 1960 since then the importance of dissolution test has grown rapidly as have the number of tests and demands in quality control laboratories. Dissolution testing is an official test used by pharmacopeias for evaluating drug release of solid and semisolid dosage forms. The main applications of the dissolution testing include biopharmaceut...

OBJECTIVE Oral administration of hypertonic solutions can contribute to intestinal damage in the initial stages of neonatal necrotizing enterocolitis. The purpose of this study is to determine the osmolality of oral liquid dosage forms used in a division of neonatology and to establish some recommendations for their dilution. METHOD The osmolality of 26 oral liquid dosage forms has been measu...