Background and Aim: To determine the clinical outcome complications encountered in adult patients with acute viral hepatitis A (AVH-A). Methods: This is a retrospective analysis of prospectively maintained database consecutive AVH- /or E. The study period was between 2017 2022. Adult (>18 years) symptoms laboratory investigations suggestive illness were included. Patients associated B C infecti...

BACKGROUND Hepatic angiosarcoma is a primary sarcoma of the liver, accounting for only 2% of all primary hepatic malignancies. Acute liver failure is an extremely rare presentation of a primary liver tumour. CASE PRESENTATION We report a case of a seventy year-old man who presented with a very short period of jaundice leading to fulminant hepatic failure (FHF). On further investigation he was...

The extent of the acute phase response and the relation between acute phase proteins and cytokines in plasma was investigated in 50 patients with fulminant hepatic failure. On admission, C reactive protein was significantly higher in fulminant hepatic failure (median: 12.4 micrograms/ml, range:0.2-112 micrograms/ml) than in 20 controls (median: 0.8 microgram/ml, range: 0.3-2.9 micrograms/ml, p ...

A grade 4/6 systolic murmur, systolic anterior motion of the mitral valve (SAM), and severe mitral regurgitation (MR) documented by two-dimensional Doppler echocardiography developed suddenly on the structurally normal heart of a patient with idiopathic portal hypertension. The patient did not have signs of congestive heart failure and the aforementioned phenomenon disappeared completely when t...

Background. Hepatic angiosarcoma is a rare and aggressive tumor that often presents at an advanced stage with nonspecific symptoms. Objective. To report a case of primary hepatic angiosarcoma in an otherwise healthy man with normal liver function tests two months prior to presenting with a short period of jaundice that progressed to fulminant hepatic failure. Methods. Case report and review of ...

A new type of activated charcoal for the direct hemoperfusion (DHP) has been developed for use in treatment of fulminant hepatic failure. Bead-type activated charcoal from petroleum pitch (BAC) was coated with polyetherurethane. The coating has permitted the charcoal to minimize the number of released microparticles and yet to show nearly the same adsorption performance as that of the non-coate...

PURPOSE Management of acetaminophen overdose focuses on the risk hepatic failure. However, acute renal failure, although less frequent, can lead to serious metabolic complications and require hemodialysis. We report three cases of acute renal failure related to acetaminophen overdose. CLINICAL FEATURES Three patients, aged 17-46 yr ingested acetaminophen 19 to 32 g, and were admitted to the i...

The high metabolic activity of the liver results in a high perfusion rate of 1 mL/g/min. Under resting conditions, this is about a quarter of the bodýs total blood supply. The oxygen-rich blood of the hepatic artery contributes to about a quarter of the total liver perfusion that may rise substantially under conditions of excessive oxygen demand. The complex blood supply makes the liver extraor...

The histological findings of fulminant hepatic failure were correlated to the demographic, clinical, biochemical and virological features in children and adolescents, native to the Amazonas State in Northern Brazil. 96.2% had evidence of infection by primary hepatotrophic viruses. Histological analysis revealed three distinct patterns of fulminant hepatic failure.

Mild hepatic dysfunction in dengue haemorrhagic fever is not unusual. However, acute liver failure (ALF) is rare. When present, its management according to most current guidelines is supportive and carries a poor prognosis. We present a patient with dengue haemorrhagic fever complicated acute liver failure and hepatic encephalopathy who was successfully treated with N-Acetylcysteine (NAC) leadi...