In the present study, the metabolites present in the leaves of Solanum anguivi was extracted using ethyl acetate. HEpG-2 and MCF-7 cell lines were collected from NCCS. The ethyl acetate extract of the Solanum anguivi was analyzed for its antiproliferative activity against the cell lines using MTT assay at various concentrations. The cell viability was reduced upto 50% at the concentration of 0....

We assemble a few remarks on the supergravity solution of hep-th/0007191, whose UV asymptotic form was previously found in hep-th/0002159. First, by normalizing the R-R fluxes, we compare the logarithmic flow of couplings in supergravity with that in field theory, and find exact agreement. We also write the 3-form field strength G3 = F3 − τH3 present in the solution in a manifestly SO(4) invari...

We provide a manifestly N = 2 supersymmetric formulation of the N = 2 U(Nc) gauge model constructed in terms of N = 1 superfields in hep-th/0409060. The model is composed of N = 2 vector multiplets in harmonic superspace and can be viewed as the N = 2 U(Nc) Yang-Mills effective action equipped with the electric and magnetic Fayet-Iliopoulos terms. We generalize this gauge model to an N = 2 U(Nc...

We derive the gravitational Hamiltonian starting from the Gauss-Bonnet action, keeping track of all surface terms. This is done using the language of orthonormal frames and forms to keep things as tidy as possible. The surface terms in the Hamiltonian give a remarkably simple expression for the total energy of a spacetime. This expression is consistent with energy expressions found in hep-th/02...

Efficient and accurate safety assessment of compounds is extremely important in the preclinical development of drugs especially when hepatotoxicity is in question. Multiparameter and time resolved assays are expected to greatly improve the prediction of toxicity by assessing complex mechanisms of toxicity. An integrated approach is presented in which Hep G2 cells and primary rat hepatocytes are...

Intercellular ligand-receptor recognitions are crucial natural interactions that initiate a number of biological and pathological events. We present here the simple construction of a unique class of biomimetic interfaces based on a graphene-mediated self-assembly of glycosyl anthraquinones to a screen-printed electrode for the detection of transmembrane glycoprotein receptors expressed on a hep...

A series of novel 13- to 15-member hydroxyproline-based macrocycles, which contain alkyl-alkyl ether and alkyl-aryl ether moieties, have been synthesized by the strategy of macrocyclization utilising azide-alkyne cycloaddition, Mitsunobu protocol and amide formation. Their anti-tumor activities towards A549, MDA-MB-231 and Hep G2 cells were screened in vitro by an MTT assay. The results indicat...

Abstract Background Treating cancer is challenging for both the patient and physician. This may be explained by fact that treatment regimens rely on either chemotherapy alone or a combination with radiotherapy. Both modalities have damaging side effects add to suffer. inconvenience from part has led scientists search discovering new era in management. Plant extracts proved beneficial many medic...