Abstract Background Multiple transfusions in thalassemia patients may lead to antibody production against blood group antigens and hemolytic transfusion reaction might occur. In this study, antibody screening test was performed by tube and gel methods to determine the prevalence and specificity of alloantibodies in thalassemia patients. Materials and Methods In this cross-sectional study, overa...

Between 1950 and 1970 there was a steady decline in the number of infant deaths from rhesus haemolytic disease of the newborn in the Yorkshire Region but no decrease in the number of pregnant women with antibodies. Following the introduction of Rh prophylaxis in 1970, the number of pregnant women sensitized has decreased by 70% and the number of infant deaths by 96%. The number of infants requi...

BACKGROUND Multiple transfusions in thalassemia patients may lead to antibody production against blood group antigens and hemolytic transfusion reaction might occur. In this study, antibody screening test was performed by tube and gel methods to determine the prevalence and specificity of alloantibodies in thalassemia patients. MATERIALS AND METHODS In this cross-sectional study, overall of 1...

Objective: To analyze the impact of implementation technical supervision in Transfusion Agencies (TAs) public blood network hospitals Federal District (DF) on hemovigilance activities, from 2009 to 2019. Methods: Retrospective descriptive cross-sectional study with a quantitative approach. Two secondary databases were used: one information Reactions (TRs) registered System Notifications Health ...

H EMOLYTIC DISEASE of the uiewhorn infant due to maternal sensitization to the Hr i)lood factor is no longer au unusual event. Case repou’ts 013 this subject, however, are infrequeuit and iui some iuistances lack sufficient information to elucidate the role of this factor in the pathogenesis of this (lisease. Though some evidence on the occurrence of hemolytic transfusion reactions due to Hr se...

Patients with autoimmune haemolytic anaemia (AIHA) frequently have anaemia of sufficient severity as to require a blood transfusion. However, it is impossible to find compatible blood when, as is frequently the case, the autoantibody in the patient's serum reacts with all normal red blood cells. Further, the autoantibody may mask the presence of a red cell alloantibody capable of causing a haem...

Sickle cell anemia (SCA) is a genetic disorder characterized by homozygous hemoglobin S (Hb S), chronic hemolytic anemia and painful episodes.1 Patients with SCA usually require red blood cell (RBC) transfusions to manage complications and to reduce morbidity during surgical procedures.1 One possible complication of multiple transfusions is alloimmunization, which occurs due to the recognition ...